hnmt
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  • Official Full Name
  • histamine N-methyltransferase
  • Background
  • In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene.
  • Synonyms
  • HNMT; histamine N-methyltransferase; HMT; HNMT-S1; HNMT-S2
Cat.#:HNMT-4898HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human HNMT Protein, GST-tagged
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Cat.#:HNMT-1704HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Histamine N-Methyltransferase, His-tagged
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Cat.#:HNMT-13863HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human HNMT, His-tagged
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Cat.#:HNMT-1811HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human HNMT, GST tagged
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Cat.#:HNMT-22HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human HNMT protein, His-tagged
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Cat.#:HNMT-27547THTag:
Source (Host):Species:Human
Product nameRecombinant Human HNMT
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Cat.#:HNMT-2878RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat HNMT Protein
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Cat.#:HNMT-2116RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey HNMT Protein, His-tagged
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Cat.#:HNMT-5216CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken HNMT
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Cat.#:HNMT-1058ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish HNMT
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Cat.#:HNMT-1355RTag:
Source (Host):Rat KidneySpecies:Rat
Product nameNative Rat HNMT Protein
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Cat.#:HNMT-5455HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human HNMT 293 Cell Lysate
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Involved Pathway

HNMT involved in several pathways and played different roles in them. We selected most pathways HNMT participated on our site, such as Histidine metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with HNMT were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Histidine metabolism
MAOB; HNMT; ALDH3A2; ALDH9A1B; FTCD; ALDH1B1; ALDH3A2A; ALDH2.1; ALDH2.2; UROC1

Protein Function

HNMT has several biochemical functions, for example, histamine N-methyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by HNMT itself. We selected most functions HNMT had, and list some proteins which have the same functions with HNMT. You can find most of the proteins on our site.
Function
Related Protein
Function histamine N-methyltransferase activity
Related Protein HNMT

Interacting Protein

HNMT has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HNMT here. Most of them are supplied by our site. Hope this information will be useful for your research of HNMT.
TERF1; CAMK2D; TINF2; POT1; Tpm1