hsp90b1
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  • Official Full Name
  • heat shock protein 90kDa beta (Grp94), member 1
  • Background
  • This gene encodes a member of a family of adenosine triphosphate(ATP)-metabolizing molecular chaperones with roles in;stabilizing and folding other proteins. The encoded protein is localized to melanosomes and the endoplasmic reticulum.;Expression of this protein is associated with a variety of pathogenic states, including tumor formation. There is a;microRNA gene located within the 5 exon of this gene. There are pseudogenes for this gene on chromosomes 1 and 15.
  • Synonyms
  • HSP90B1; heat shock protein 90kDa beta (Grp94), member 1; TRA1, tumor rejection antigen (gp96) 1; endoplasmin; GP96; GRP94; GRP-94; gp96 homolog; tumor rejection antigen 1; 94 kDa glucose-regulated protein; Tumor rejection antigen-1 (gp96); tumor rejection antigen (gp96) 1; glucose regulated protein, 94 kDa; endothelial cell (HBMEC) glycoprotein; heat shock protein 90 kDa beta member 1; ECGP; TRA1
Cat.#:HSP90B1-07HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Heat Shock Protein 90kDa Beta (Grp94), Member 1
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Cat.#:HSP90B1-132HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human HSP90B1 protein, His-tagged
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Cat.#:HSP90B1-138HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human HSP90B1 protein, MYC/DDK-tagged
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Cat.#:HSP90B1-27413THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human HSP90B1, His-tagged
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Cat.#:HSP90B1-338HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Heat Shock Protein 90kDa Beta (Grp94), Member 1
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Cat.#:HSP90B1-7779HTag:His/T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human HSP90B1 protein, His & T7-tagged
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Cat.#:Hsp90b1-26MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Hsp90b1 protein, His-tagged
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Cat.#:HSP90B1-7899MTag:His/myc
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Hsp90b1 protein, His/myc-tagged
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Cat.#:HSP90B1-2941RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat HSP90B1 Protein
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Cat.#:HSP90B1-605CTag:His
Source (Host):Mammalian CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus HSP90B1 Protein, His-tagged
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Cat.#:HSP90B1-2162RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey HSP90B1 Protein, His-tagged
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Cat.#:HSP90B1-524CTag:
Source (Host):Insect cellsSpecies:Canine
Product nameRecombinant Canine HSP90B1 protein
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Cat.#:HSP90B1-5862CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken HSP90B1
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Cat.#:HSP90B1-9805ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish HSP90B1
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Cat.#:HSP90B1-5360HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human HSP90B1 293 Cell Lysate
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Involved Pathway

HSP90B1 involved in several pathways and played different roles in them. We selected most pathways HSP90B1 participated on our site, such as Protein processing in endoplasmic reticulum, PIK-Akt signaling pathway, NOD-like receptor signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with HSP90B1 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Protein processing in endoplasmic reticulum
MAPK8B; HSPA5; STT3B; HSPA1B; STT3A; MAPK9; DNAJC10; DNAJB12A; FBXO2; SSR4
PIK-Akt signaling pathway
HSP90AA1; COL27A1; FGFR2; SGK3; TNR; AKT1; GNG4; VWF; LPAR4; LAMC1
NOD-like receptor signaling pathway
CXCL1; MAPK14A; MAPK12B; NAIP1; LOC100033925; MAPK8; TNFAIP3; HSP90AA1; CXCL2; ERBB2IP
Estrogen signaling pathway
ATF4; PLCB1; GNAO1; GNAS; FKBP5; PIK3CA; PIK3R3; HSP90B1; KCNJ6; Adcy4
Thyroid hormone synthesis
CREB3L1; GSR; GPX6; ATP1B1; ATP1A4; ATP1A2; ATP1A1; ASGR2; SLC26A4; TPO
Pathways in cancer
LAMA3; GNA11; PDGFRA; BIRC7; LAMA5; MAP2K2; TCEB1; F2RL3; RAD51; SMO
Prostate cancer
PDGFRA; HRAS; SMARCC2; GRB2; PIK3R2; KRAS; IKBKG; PDGFB; BAD; PDGFA

Protein Function

HSP90B1 has several biochemical functions, for example, ATP binding, RNA binding, calcium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HSP90B1 itself. We selected most functions HSP90B1 had, and list some proteins which have the same functions with HSP90B1. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein ATP2B1; AAK1; DCAKD; CKBA; ETNK2; UBE2E2; TTL; ATP7B; CDK15; SNRKA
Function RNA binding
Related Protein SPI1; ZNF74; EIF3B; MKI67IP; HDLBPA; AHCYL1; RPL6; RPL13; ARHGEF28; LSM5
Function calcium ion binding
Related Protein EMR3; FAT1A; CABP1; PVALB5; S100A1; ITIH1; FKBP10B; SLC25A24; CLSTN1; CDH15
Function low-density lipoprotein particle receptor binding
Related Protein ARRB2; SYT1; LANCL1; APOB; APOE; APOEB; LDLRAP1; CRP; APOA5; LRP2
Function protein binding
Related Protein CEP76; COL6A2; ORMDL3; NIPAL3; PACSIN1; C1orf187; SYCE3; ENDOG; MCM8; SORBS2
Function protein phosphatase binding
Related Protein ROS1; JUP; NEK2; MAPK14; DLG3; EGFR; DRD1; ERBB2; GRB2; STAT3
Function unfolded protein binding
Related Protein GRPEL2; GRXCR2; HSPA5; SIL1; HSP90AA1.1; NDUFAF1; CLPXA; TTC1; ST13; H2-KE2
Function virion binding
Related Protein PTX3; APCS; CLEC4M; CD209; PPIA; HIPK2; TSG101; HSP90B1; PVRL1

Interacting Protein

HSP90B1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HSP90B1 here. Most of them are supplied by our site. Hope this information will be useful for your research of HSP90B1.
FANCC; PPIB; FOS; SOD2; TNFRSF1B; NR4A1; CHM; RXRB; EEF1D; MDM2; UBA5; SIRT3; EIF2AK3; GAMMAHV.ORF40; GAMMAHV.M9; EGFR; POLR2E