hsp90b1
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  • Official Full Name
  • heat shock protein 90kDa beta (Grp94), member 1
  • Background
  • This gene encodes a member of a family of adenosine triphosphate(ATP)-metabolizing molecular chaperones with roles in;stabilizing and folding other proteins. The encoded protein is localized to melanosomes and the endoplasmic reticulum.;Expression of this protein is associated with a variety of pathogenic states, including tumor formation. There is a;microRNA gene located within the 5 exon of this gene. There are pseudogenes for this gene on chromosomes 1 and 15.
  • Synonyms
  • HSP90B1; heat shock protein 90kDa beta (Grp94), member 1; TRA1, tumor rejection antigen (gp96) 1; endoplasmin; GP96; GRP94; GRP-94; gp96 homolog; tumor rejection antigen 1; 94 kDa glucose-regulated protein; Tumor rejection antigen-1 (gp96); tumor rejection antigen (gp96) 1; glucose regulated protein, 94 kDa; endothelial cell (HBMEC) glycoprotein; heat shock protein 90 kDa beta member 1; ECGP; TRA1
Cat.#:HSP90B1-07HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Heat Shock Protein 90kDa Beta (Grp94), Member 1
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Cat.#:HSP90B1-132HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human HSP90B1 protein, His-tagged
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Cat.#:HSP90B1-138HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human HSP90B1 protein, MYC/DDK-tagged
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Cat.#:HSP90B1-27413THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human HSP90B1, His-tagged
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Cat.#:HSP90B1-338HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Heat Shock Protein 90kDa Beta (Grp94), Member 1
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Cat.#:HSP90B1-7779HTag:His/T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human HSP90B1 protein, His & T7-tagged
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Cat.#:Hsp90b1-26MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Hsp90b1 protein, His-tagged
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Cat.#:HSP90B1-7899MTag:His/myc
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Hsp90b1 protein, His/myc-tagged
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Cat.#:HSP90B1-2941RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat HSP90B1 Protein
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Cat.#:HSP90B1-605CTag:His
Source (Host):Mammalian CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus HSP90B1 Protein, His-tagged
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Cat.#:HSP90B1-2162RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey HSP90B1 Protein, His-tagged
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Cat.#:HSP90B1-524CTag:
Source (Host):Insect cellsSpecies:Canine
Product nameRecombinant Canine HSP90B1 protein
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Cat.#:HSP90B1-5862CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken HSP90B1
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Cat.#:HSP90B1-9805ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish HSP90B1
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Cat.#:HSP90B1-5360HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human HSP90B1 293 Cell Lysate
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Involved Pathway

HSP90B1 involved in several pathways and played different roles in them. We selected most pathways HSP90B1 participated on our site, such as Protein processing in endoplasmic reticulum, PIK-Akt signaling pathway, NOD-like receptor signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with HSP90B1 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Protein processing in endoplasmic reticulum
ATF6; MAP2K7; NFE2L2; HSPA1B; CALR; BCL2; SIL1; FBXO6; NGLY1; UBE2D1B
PIK-Akt signaling pathway
TCL1B1; COL24A1; IFNA8; SGK3; IFNA12; THBS3; PKN2; LAMA4; VEGFA; CCNE2
NOD-like receptor signaling pathway
IL1B; MAPK12; CASP1; MAP3K7IP3; HSP90AB1; TAB2; NAIP1; RELA; NLRP3; IL18
Estrogen signaling pathway
ESR2; SHC4; PIK3CD; SP1; SHC3; PLCB2; PIK3R1; MAPK3; SOS1; HSPA1L
Thyroid hormone synthesis
GPX6; TTF2; GNAS; Adcy4; TSHB; PRKCB; ATP1A4; PLCB1; ATP1B2; CREB3L1
Pathways in cancer
MLH1; CBLB; PDGFA; BIRC5; FZD10; WNT7B; PIK3CB; FGFR3; MAPK8; BDKRB1
Prostate cancer
MAP4K1; HRAS; TRP53; MAPK3; CPN1; PDGFRB; ARID1A; CREB3L1; PIK3R2; NKX3

Protein Function

HSP90B1 has several biochemical functions, for example, ATP binding, RNA binding, calcium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HSP90B1 itself. We selected most functions HSP90B1 had, and list some proteins which have the same functions with HSP90B1. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein IRAK3; ZAP70; XRCC3; GSS; NIM1K; KIAA1804; MKKS; UBE1Y1; EPHA2A; PAK4
Function RNA binding
Related Protein RBM6; PUS10; RPLP1; THOC7; HNRNPM; EIF4H; RPS15A; RPL31; IREB2; RBM44
Function calcium ion binding
Related Protein NCS1A; CDH15; MMP20; MYL1; ANXA3; SLC25A24; PCDH2AB9; CAMKK2; S100V2; C2CD4A
Function low-density lipoprotein particle receptor binding
Related Protein LRPAP1; ARRB2; DNAJA1; SLC9A3R2; SNX17; APOB; SYT1; APOEA; LRP2; AP2M1
Function protein binding
Related Protein FAM20C; FAM3C; ALOX5; PPP2R2A; MED19; C14orf118; ANKRD45; SEPSECS; HPSE; RAPGEF6
Function protein phosphatase binding
Related Protein AP3B1; GNB2L1; PPP1R3G; VCP; TRAF2; PPP6R1; ROS1; GRB2; ANAPC4; CSK
Function unfolded protein binding
Related Protein ERLEC1; DNAJA2L; SIL1; TUBB4B; DNAJB1A; HSPE1; AIPL1; H2-KE2; HSP90AA1.2; CALR
Function virion binding
Related Protein HIPK2; APCS; CLEC4M; HSP90B1; TSG101; CD209; PVRL1; PTX3; PPIA

Interacting Protein

HSP90B1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HSP90B1 here. Most of them are supplied by our site. Hope this information will be useful for your research of HSP90B1.
FANCC; PPIB; FOS; SOD2; TNFRSF1B; NR4A1; CHM; RXRB; EEF1D; MDM2; UBA5; SIRT3; EIF2AK3; GAMMAHV.ORF40; GAMMAHV.M9; EGFR; POLR2E