Recombinant Human HSP90B1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: HSP90B1-4761H
• Product Overview: HSP90B1 MS Standard C13 and N15-labeled recombinant protein (NP_003290) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a member of a family of adenosine triphosphate(ATP)-metabolizing molecular chaperones with roles in stabilizing and folding other proteins. The encoded protein is localized to melanosomes and the endoplasmic reticulum. Expression of this protein is associated with a variety of pathogenic states, including tumor formation. There is a microRNA gene located within the 5' exon of this gene. There are pseudogenes for this gene on chromosomes 1 and 15.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 92.5 kDa
• AA Sequence: MRALWVLGLCCVLLTFGSVRADDEV DVDGTVEEDLGKSREGSRTDDEVVQ REEEAIQLDGLNASQIRELREKSEK FAFQAEVNRMMKLIINSLYKNKEIF LRELISNASDALDKIRLISLTDENA LSGNEELTVKIKCDKEKNLLHVTDT GVGMTREELVKNLGTIAKSGTSEFL NKMTEAQEDGQSTSELIGQFGVGFY SAFLVADKVIVTSKHNNDTQHIWES DSNEFSVIADPRGNTLGRGTTITLV LKEEASDYLELDTIKNLVKKYSQFI NFPIYVWSSKTETVEEPMEEEEAAK EEKEESDDEAAVEEEEEEKKPKTKK VEKTVWDWELMNDIKPIWQRPSKEV EEDEYKAFYKSFSKESDDPMAYIHF TAEGEVTFKSILFVPTSAPRGLFDE YGSKKSDYIKLYVRRVFITDDFHDM MPKYLNFVKGVVDSDDLPLNVSRET LQQHKLLKVIRKKLVRKTLDMIKKI ADDKYNDTFWKEFGTNIKLGVIEDH SNRTRLAKLLRFQSSHHPTDITSLD QYVERMKEKQDKIYFMAGSSRKEAE SSPFVERLLKKGYEVIYLTEPVDEY CIQALPEFDGKRFQNVAKEGVKFDE SEKTKESREAVEKEFEPLLNWMKDK ALKDKIEKAVVSQRLTESPCALVAS QYGWSGNMERIMKAQAYQTGKDIST NYYASQKKTFEINPRHPLIRDMLRR IKEDEDDKTVLDLAVVLFETATLRS GYLLPDTKAYGDRIERMLRLSLNID PDAKVEEEPEEEPEETAEDTTEDTE QDEDEEMDVGTDEEEETAKESTAEK DELTRTRPLEQKLISEEDLAANDIL DYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: HSP90B1 heat shock protein 90 beta family member 1 [ Homo sapiens (human) ]
• Official Symbol: HSP90B1
• Synonyms: HSP90B1; heat shock protein 90kDa beta (Grp94), member 1; TRA1, tumor rejection antigen (gp96) 1; endoplasmin; GP96; GRP94; GRP-94; gp96 homolog; tumor rejection antigen 1; 94 kDa glucose-regulated protein; Tumor rejection antigen-1 (gp96); tumor rejection antigen (gp96) 1; glucose regulated protein, 94 kDa; endothelial cell (HBMEC) glycoprotein; heat shock protein 90 kDa beta member 1; ECGP; TRA1
• Gene ID: 7184
• mRNA Refseq: NM_003299
• Protein Refseq: NP_003290
• MIM: 191175
• UniProt ID: P14625