icam3
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  • Official Full Name
  • intercellular adhesion molecule 3
  • Background
  • The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. [provided by RefSeq, Jul 2008]
  • Synonyms
  • ICAM3; intercellular adhesion molecule 3; CD50; CDW50; ICAM-R; ICAM-3; intercellular adhesion molecule-3
Cat.#:ICAM3-796HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human ICAM3 Protein, MYC/DDK-tagged
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Cat.#:ICAM3-14032HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ICAM3, His-tagged
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Cat.#:ICAM3-1627HTag:N/A
Source (Host):NS0Species:Human
Product nameRecombinant Human Intercellular Adhesion Molecule 3
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Cat.#:ICAM3-2754HTag:His/T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ICAM3 protein, His & T7-tagged
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Cat.#:ICAM3-2755HTag:His/T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ICAM3 protein, His & T7-tagged
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Cat.#:ICAM3-3164HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human ICAM3, His tagged
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Cat.#:ICAM3-493HTag:Fc Chimera
Source (Host):NSO cellsSpecies:Human
Product nameRecombinant Human ICAM3, Fc Chimera
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Cat.#:ICAM3-655HTag:FC/His
Source (Host):HEK293Species:Human
Product nameRecombinant Human Intercellular Adhesion Molecule 3, Fc-His
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Cat.#:ICAM3-2186RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey ICAM3 Protein, His-tagged
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Cat.#:ICAM3-2417HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human ICAM3 cell lysate
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Cat.#:ICAM3-2935HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human ICAM3 cell lysate
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Involved Pathway

ICAM3 involved in several pathways and played different roles in them. We selected most pathways ICAM3 participated on our site, such as Cell adhesion molecules (CAMs), which may be useful for your reference. Also, other proteins which involved in the same pathway with ICAM3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cell adhesion molecules (CAMs)
SELL; CD2; Ntng2; ITGAV; HLA-DMB; CLDNF; NRXN1A; CNTN1; CLDNJ; HLA-F

Protein Function

ICAM3 has several biochemical functions, for example, integrin binding, protein binding, receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ICAM3 itself. We selected most functions ICAM3 had, and list some proteins which have the same functions with ICAM3. You can find most of the proteins on our site.
Function
Related Protein
Function integrin binding
Related Protein ANGPTL3; ILK; FN1A; CYR61L1; TLN1; CIB2; AMICA1; THY1; ADAMTS13; EGFL6
Function protein binding
Related Protein KRT16; HNRNPC; IL15; TMEM174; VAV1; RABEP1; NFE2L3; TMEM110; SNTB1; ARGLU1
Function receptor binding
Related Protein NRG4; TNFSF12; PLA2G1B; PCSK1N; ADAM10; VTCN1; F2; NRG3; ECH1; MPV17L

Interacting Protein

ICAM3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ICAM3 here. Most of them are supplied by our site. Hope this information will be useful for your research of ICAM3.
ITGAL; ZBTB16; mhpD1

ICAM3 Related Articles

Park, KT; Burnett, S; et al. Development and characterization of a monoclonal antibody specific for bovine CD209. VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY 163:216-220(2015).
Liu, P; Wang, X; et al. Low Copy Numbers of DC-SIGN in Cell Membrane Microdomains: Implications for Structure and Function. TRAFFIC 15:179-196(2014).