| Description : |
The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
59.5 kDa |
| AA Sequence : |
MATMVPSVLWPRACWTLLVCCLLTP GVQGQEFLLRVEPQNPVLSAGGSLF VNCSTDCPSSEKIALETSLSKELVA SGMGWAAFNLSNVTGNSRILCSVYC NGSQITGSSNITVYRLPERVELAPL PPWQPVGQNFTLRCQVEDGSPRTSL TVVLLRWEEELSRQPAVEEPAEVTA TVLASRDDHGAPFSCRTELDMQPQG LGLFVNTSAPRQLRTFVLPVTPPRL VAPRFLEVETSWPVDCTLDGLFPAS EAQVYLALGDQMLNATVMNHGDTLT ATATATARADQEGAREIVCNVTLGG ERREARENLTVFSFLGPIVNLSEPT AHEGSTVTVSCMAGARVQVTLDGVP AAAPGQPAQLQLNATESDDGRSFFC SATLEVDGEFLHRNSSVQLRVLYGP KIDRATCPQHLKWKDKTRHVLQCQA RGNPYPELRCLKEGSSREVPVGIPF FVNVTHNGTYQCQASSSRGKYTLVV VMDIEAGSSHFVPVFVAVLLTLGVV TIVLALMYVFREHQRSGSYHVREES TYLPLTSMQPTEAMGEEPSRAETRT RPLEQKLISEEDLAANDILDYKDDD DKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
