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Recombinant Human ICAM3 protein, His & T7-tagged

Cat.No. : ICAM3-2755H
Product Overview : Recombinant Human ICAM3 aa. (Gly46~Gln197 (Accession # P32942)) fused with N-terminal His & T7 tag was produced in E. coli cells.
  • Specification
  • Gene Information
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Description : The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. Alternative splicing results in multiple transcript variants encoding different isoforms.
Source : E. coli
Species : Human
Tag : His & T7
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 20.2kDa
Protein length : Gly46~Gln197 (Accession # P32942)
Endotoxin : <1.0EU per 1µg (determined by the LAL method)
Purity : >95%
Characteristic : The isoelectric point is 4.7.
Applications : SDS-PAGE; WB; ELISA; IP
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage buffer : Supplied as lyophilized form in 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5% trehalose, and preservative.
Reconstitution : Reconstitute in sterile ddH2O.
Gene Name : ICAM3 intercellular adhesion molecule 3 [ Homo sapiens (human) ]
Official Symbol : ICAM3
Synonyms : CD50; CDW50; ICAM-R; ICAM-3; intercellular adhesion molecule 3
Gene ID : 3385
mRNA Refseq : NM_001320605.1
Protein Refseq : NP_001307534.1
UniProt ID : P32942

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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