ifi30
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  • Official Full Name
  • IFI30 interferon, gamma-inducible protein 30 [ Homo sapiens ]
  • Background
  • The protein encoded by this gene is a lysosomal thiol reductase that at low pH can reduce protein disulfide bonds. The enzyme is expressed constitutively in antigen-presenting cells and induced by gamma-interferon in other cell types. This enzyme has an important role in MHC class II-restricted antigen processing.
  • Synonyms
  • interferon, gamma-inducible protein 30; 5398; Ensembl:ENSG00000216490; MGC32056; gamma-interferon-inducible lysosomal thiol reductase; legumaturain; gamma-interferon-inducible protein IP-30; interferon gamma-inducible protein 30 preproprotein; GILT; IP30; IFI-30
Cat.#:IFI30-991HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human IFI30 Protein, MYC/DDK-tagged
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Cat.#:IFI30-1317HTag:His/T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human IFI30 protein, His & T7-tagged
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Cat.#:IFI30-14061HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human IFI30, GST-tagged
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Cat.#:IFI30-468HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human IFI30 Protein, His-tagged
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Cat.#:IFI30-8009MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse IFI30 Protein
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Cat.#:IFI30-2993RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat IFI30 Protein
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Cat.#:IFI30-1567ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish IFI30
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Cat.#:IFI30-7185HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Interferon, Gamma-Inducible Protein 30, His-tagged
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Cat.#:IFI30-1503HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human IFI30 cell lysate
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Involved Pathway

IFI30 involved in several pathways and played different roles in them. We selected most pathways IFI30 participated on our site, such as Adaptive Immune System, Antigen processing and presentation, Cytokine Signaling in Immune system, which may be useful for your reference. Also, other proteins which involved in the same pathway with IFI30 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Adaptive Immune System
FGF18B; FAM49BA; MGC174857; CLEC2D; SIGLEC9; BLK; SEC61B; CLEC2G; KIF2C; SRMS
Antigen processing and presentation
CD8A; RFXANK; LGMN; HLA-DRB1; KIR2DL1; IFI30; NFYA; HLA-E; HLA-G; HSPA4
Cytokine Signaling in Immune system
CSF2; OSTN; DUSP7; NUP50; LAMTOR2; PELI3; GBP5; TRIM45; IRF6; UBE2V1
Immune System
PANX1; POLR3H; CD160; LILRA1; TRIM48; SH3RF1; RNF220; IRF6; DEFB129; KLHL21
Interferon Signaling
EIF4G2; TRIM29; TRIM45; GBP4; MX2; GBP2; BST2; IFIT8; IFIT14; GBP1
Interferon gamma signaling
GBP4; GBP1; TRIM10; TRIM62; HLA-DQB2; TRIM26; TRIM14; TRIM3; FCGR1B; OASL
MHC class II antigen presentation
OSBPL1A; KLC3; RACGAP1; CTSLL; FAM49BA; CTS7; DYNC1I1; KIFAP3; IFI30; CTSE

Protein Function

IFI30 has several biochemical functions, for example, oxidoreductase activity, acting on a sulfur group of donors, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IFI30 itself. We selected most functions IFI30 had, and list some proteins which have the same functions with IFI30. You can find most of the proteins on our site.
Function
Related Protein
Function oxidoreductase activity, acting on a sulfur group of donors
Related Protein IFI30; SRX1
Function protein binding
Related Protein PASK; ARL6IP5; ATP6V0D2; ZKSCAN4; RFPL4; FOXO3; BLOC1S4; INTS9; CHAF1A; GRM2

Interacting Protein

IFI30 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IFI30 here. Most of them are supplied by our site. Hope this information will be useful for your research of IFI30.
NOTCH2NL; KRTAP4-12; mutT7; DAPK1; Cnot2; KIFAP3; Sept6

IFI30 Related Articles

Cheluvappa, R; Eri, R; et al. Modulation of Interferon Activity-Associated Soluble Molecules by Appendicitis and Appendectomy Limits Colitis-Identification of Novel Anti-Colitic Targets. JOURNAL OF INTERFERON AND CYTOKINE RESEARCH 35:108-115(2015).
Metsalu, T; Viltrop, T; et al. Using RNA sequencing for identifying gene imprinting and random monoallelic expression in human placenta. EPIGENETICS 9:1397-1409(2014).