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Official Full Name IFI30 interferon, gamma-inducible protein 30 [ Homo sapiens ]
Background The protein encoded by this gene is a lysosomal thiol reductase that at low pH can reduce protein disulfide bonds. The enzyme is expressed constitutively in antigen-presenting cells and induced by gamma-interferon in other cell types. This enzyme has an important role in MHC class II-restricted antigen processing.
Synonyms interferon, gamma-inducible protein 30; 5398; Ensembl:ENSG00000216490; MGC32056; gamma-interferon-inducible lysosomal thiol reductase; legumaturain; gamma-interferon-inducible protein IP-30; interferon gamma-inducible protein 30 preproprotein; GILT; IP30; IFI-30
    • Species :
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Human Cell
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • T7
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human IFI30-1317H Recombinant Human IFI30 protein, His & T7-tagged E.coli His/T7
    Human IFI30-14061H Recombinant Human IFI30, GST-tagged E.coli GST
    Human IFI30-1503HCL Recombinant Human IFI30 cell lysate Human Cell N/A
    Human IFI30-468H Recombinant Human IFI30 Protein, His-tagged HEK293 His
    Human IFI30-7185H Recombinant Human Interferon, Gamma-Inducible Protein 30, His-tagged E.coli His
    Human IFI30-991H Recombinant Human IFI30 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Mouse IFI30-8009M Recombinant Mouse IFI30 Protein Mammalian Cell His
    Rat IFI30-2993R Recombinant Rat IFI30 Protein Mammalian Cell His
    Zebrafish IFI30-1567Z Recombinant Zebrafish IFI30 Mammalian Cell His

    IFI30 involved in several pathways and played different roles in them. We selected most pathways IFI30 participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with IFI30 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Adaptive Immune System CTSL2; ASB2; AP2M1; UFL1; KIF4; TREM1; IGKV1-5; KLHL20; HCST; AP1B1
    Antigen processing and presentation HLA-DQA2; CANX; KLRD1; PSME1; CTSL1; CD8B1; HLA-DMA; KIR2DL3; HSPA4; KIR2DL1
    Cytokine Signaling in Immune system TRIM8; CASPBL; NRG4; EIF4EB; CASPB; GBP6; FGFR1B; UBE2L6; ADAR; NEFLB
    Immune System AGER; MASP2; CD200R3; BTR30; LAT2; CYBA; IFIT10; KLRB1A; LRSAM1; SEC61B
    Interferon Signaling TRIM22; GBP1; TRIM46; IFIT12; TRIM14; TRIM6; IFITM2; IFI6; SAMHD1; MX2
    Interferon gamma signaling TRIM45; TRIM62; TRIM8; GBP6; HLA-DQB2; GBP4; IRF6; FCGR1B; TRIM14; GBP1
    MHC class II antigen presentation MGC174155; KLC3; KIF26A; DYNC1I1; KIF22; KIF15; KIFAP3; DCTN6; CTSH; CTSO

    IFI30 has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by IFI30 itself. We selected most functions IFI30 had, and list some proteins which have the same functions with IFI30. You can find most of the proteins on our site.

    Function Related Protein
    oxidoreductase activity, acting on a sulfur group of donors IFI30; SRX1
    protein binding ZBTB44; SHISA5; BTF3; HIF1AN; HERPUD1; SLC2A4; SUMO2; TDP1; IPO7; RASSF2

    IFI30 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IFI30 here. Most of them are supplied by our site. Hope this information will be useful for your research of IFI30.

    NOTCH2NL; KRTAP4-12; mutT7; DAPK1; Cnot2; KIFAP3; Sept6

    Cheluvappa, R; Eri, R; et al. Modulation of Interferon Activity-Associated Soluble Molecules by Appendicitis and Appendectomy Limits Colitis-Identification of Novel Anti-Colitic Targets. JOURNAL OF INTERFERON AND CYTOKINE RESEARCH 35:108-115(2015).
    Metsalu, T; Viltrop, T; et al. Using RNA sequencing for identifying gene imprinting and random monoallelic expression in human placenta. EPIGENETICS 9:1397-1409(2014).

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