igfbp2
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  • Official Full Name
  • insulin-like growth factor binding protein 2, 36kDa
  • Background
  • Inhibits IGF-mediated growth and developmental rates. IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
  • Synonyms
  • IGFBP2; insulin-like growth factor binding protein 2, 36kDa; IBP2; IGF-BP53; insulin-like growth factor-binding protein 2; IBP-2; IGFBP-2; IGF-binding protein 2;
Cat.#:IGFBP2-25HTag:FLAG
Source (Host):Mammalian cellSpecies:Human
Product nameRecombinant Human IGFBP2 protein, FLAG-tagged
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Cat.#:IGFBP2-1388HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human IGFBP2 Protein, MYC/DDK-tagged
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Cat.#:IGFBP2-11HTag:N/A
Source (Host):YeastSpecies:Human
Product nameRecombinant Human IGFBP2
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Cat.#:IGFBP2-29545THTag:
Source (Host):Insect cellsSpecies:Human
Product nameRecombinant Human IGFBP2 protein
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Cat.#:IGFBP2-477HTag:Met
Source (Host):NSO cellsSpecies:Human
Product nameRecombinant Human IGFBP2, Met-tagged
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Cat.#:IGFBP2-5049HTag:N/A
Source (Host):High-5 insect cellsSpecies:Human
Product nameRecombinant Human Insulin-Like Growth Factor Binding Protein 2, 36kDa
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Cat.#:IGFBP2-824HTag:His/T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human IGFBP2 protein, His & T7-tagged
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Cat.#:IGFBP2-8072MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse IGFBP2 Protein
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Cat.#:Igfbp2-825MTag:His/GST
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Igfbp2 protein, His & GST-tagged
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Cat.#:Igfbp2-969MTag:Fc
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Igfbp2 Protein, Fc-tagged
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Cat.#:Igfbp2-970MTag:His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Igfbp2 Protein, His-tagged
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Cat.#:IGFBP2-3008RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat IGFBP2 Protein
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Cat.#:Igfbp2-826RTag:His/S
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Igfbp2 protein, His & S-tagged
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Cat.#:IGFBP2-1188RTag:His
Source (Host):HEK293Species:Rhesus Macaque
Product nameRecombinant Rhesus IGFBP2 Protein, His-tagged
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Cat.#:IGFBP2-1414BTag:N/A
Source (Host):CHOSpecies:Bovine
Product nameRecombinant Bovine Insulin-Like Growth Factor Binding Protein 2, 36kDa
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Cat.#:IGFBP2-6911CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken IGFBP2
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Cat.#:Igfbp2-1749MTag:N/A
Source (Host):NS0Species:Mouse
Product nameRecombinant Mouse Insulin-like Growth Factor Binding Protein 2
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Cat.#:IGFBP2-1457CCLTag:
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant Cynomolgus IGFBP2 cell lysate
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Involved Pathway

IGFBP2 involved in several pathways and played different roles in them. We selected most pathways IGFBP2 participated on our site, such as Metabolism of proteins, Myometrial Relaxation and Contraction Pathways, Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs), which may be useful for your reference. Also, other proteins which involved in the same pathway with IGFBP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Metabolism of proteins
ST8SIA2; ASNA1; WIPI1; ADAMTS13; CNIH; CEACAM21; CNIH3; APEH; DCP2; SLC38A8
Myometrial Relaxation and Contraction Pathways
ADM; ACTA1; RAMP2; GUCA2A; RGS20; GABPA; RAMP1; RGS10; CNN2; RGS6
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
PAPPAB; IGFBP5B; IGFBP6; IGFBP1B; IGFBP5A; IGFBP5; KLK13; IGFBP6A; IGFBP4; IGF2B

Protein Function

IGFBP2 has several biochemical functions, for example, insulin-like growth factor I binding, insulin-like growth factor II binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IGFBP2 itself. We selected most functions IGFBP2 had, and list some proteins which have the same functions with IGFBP2. You can find most of the proteins on our site.
Function
Related Protein
Function insulin-like growth factor I binding
Related Protein IGF1R; IGFBP3; IGFBP5; IGFBP6A; IGFBP5B; IGFBP5A; IGFBP2A; IGFBP2; IGFBP4; INSR
Function insulin-like growth factor II binding
Related Protein IGFBP5A; IGFBP2; IGFBP1B; IGFBP3; IGFBP5B; IGFBP6B; IGFBP1A; IGFBP6A; IGFBP2A; IGFBP4
Function protein binding
Related Protein CRYAA; TSSK3; FAM133A; ITGA7; RTN4RL2B; MSTN; DNAJB5; TEAD1; BTF3; ASMTL

Interacting Protein

IGFBP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IGFBP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of IGFBP2.
INO80B; aroP; GSDMB

IGFBP2 Related Articles

Kang, Z; Yu, Y; et al. Downregulation of IGFBP2 is associated with resistance to IGF1R therapy in rhabdomyosarcoma. ONCOGENE 33:5697-5705(2014).
Strimpakos, A; Pentheroudakis, G; et al. The Prognostic Role of Ephrin A2 and Endothelial Growth Factor Receptor Pathway Mediators in Patients With Advanced Colorectal Cancer Treated With Cetuximab. CLINICAL COLORECTAL CANCER 12:267-274(2013).