| Species : |
Mouse |
| Source : |
Mammalian Cells |
| Tag : |
Non |
| Protein Length : |
1-305 a.a. |
| Description : |
Insulin-like growth factor binding protein 2, also known as IGFBP2, is an extracellular unglycosylated polypeptide that specifically binds IGF and modulates its effects. IGFBP-2 has direct effects on breast cancer proliferation via stimulation of critical signaling pathways. |
| Molecular Weight : |
The predicted molecular weight of Recombinant Mouse IGFBP-2 is Mr 29.4 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 35 kDa. |
| State Of Matter : |
Lyophilized. |
| Purity : |
>95% by SDS Page and analyzed by silver stain. |
| Formulation : |
This recombinant protein was lyophilized from a 0.2 μm filtered solution in 30% acetonitrile (CH3CN) and 0.1% trifluoroacetic acid (TFA). |
| Endotoxin : |
<1.0 EU/µg as determined by the LAL method. |
| Biological Activity : |
The biological activity of Mouse IGFBP-2 was determined by its ability to inhibit the biological activity of rmIGF-II on MCF-7 cells. The expected ED50 is typically 0.125 - 0.5 μg/ml in the presence of 30 ng/ml recombinant mouse IGF-II. |
| Storage And Stability : |
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°Cto -70°C. After aseptic reconstitution, this protein may be stored at 2°Cto 8°Cfor one month or at -20°Cto -70°Cin a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions. |
| Full Length : |
Full L. |
