inhba
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  • Official Full Name
  • inhibin, beta A
  • Background
  • Activin A is a homodimer of 14kDa beta-A. Activin A, a cytokine member of the transforming growth factor-beta superfamily, is expressed locally by the mesenchymal component of the hemopoietic microenvironment. Its expression is regulated on the mRNA level by different cytokines, and the biological activity of the protein is tightly controlled by several inhibitory molecules.1 Inhibins and activins are members of the transforming growth factor beta superfamily and are known to modulate the growth and differentiation of several cell types.2 Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins. The standard product used in this kit is recombinant Activin A, which is composed of two single chains of 116 amino acids with the molecular mass of 26KDa.
  • Synonyms
  • EDF; FRP; INHBA
Cat.#:INHBA-2404HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human INHBA Protein, MYC/DDK-tagged
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Cat.#:INHBA-5120HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human INHBA Protein, GST-tagged
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Cat.#:Activin-A-3121HTag:
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human Activin-A
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Cat.#:INHBA&INHBB-146HTag:His
Source (Host):Nicotiana benthamianaSpecies:Human
Product nameRecombinant Human INHBA&INHBB Active, His-tagged
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Cat.#:INHBA&INHBB-1544HTag:His
Source (Host):Nicotiana benthamianaSpecies:Human
Product nameRecombinant human Activin AB, Active, His-tagged
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Cat.#:INHBA&INHBB-736HTag:
Source (Host):CHO cellsSpecies:Human
Product nameRecombinant Human INHBA&INHBB
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Cat.#:INHBA&INHBC-737HTag:
Source (Host):CHO cellsSpecies:Human
Product nameRecombinant Human INHBA&INHBC
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Cat.#:INHBA/INHBB-33HTag:
Source (Host):CHOSpecies:Human
Product nameRecombinant Human INHBA/INHBB protein
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Cat.#:INHBA-131HTag:
Source (Host):Nicotiana benthamianaSpecies:Human
Product nameRecombinant Human INHBA Active
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Cat.#:INHBA-141HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human INHBA
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Cat.#:INHBA-144HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Inhibin, Beta A
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Cat.#:INHBA-145HTag:His
Source (Host):Nicotiana benthamianaSpecies:Human
Product nameRecombinant Human Inhibin Beta A chain, His tagged
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Cat.#:INHBA-1542HTag:His
Source (Host):Nicotiana benthamianaSpecies:Human
Product nameRecombinant human Activin A, Active, His-tagged
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Cat.#:INHBA-1543HTag:
Source (Host):Nicotiana benthamianaSpecies:Human
Product nameRecombinant human Activin A, Active
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Cat.#:INHBA-173HTag:His
Source (Host):Nicotiana benthamianaSpecies:Human
Product nameRecombinant Human INHBA, His-tagged
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Cat.#:INHBA-1920HTag:N/A
Source (Host):CHOSpecies:Human
Product nameRecombinant Human Activin A
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Cat.#:INHBA-267HTag:
Source (Host):Insect cellsSpecies:Human
Product nameRecombinant Human INHBA protein
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Cat.#:INHBA-268HTag:His
Source (Host):Nicotiana benthamianaSpecies:Human
Product nameRecombinant Human INHBA protein, His-tagged
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Cat.#:INHBA-276HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Inhibin A, His-tagged
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Cat.#:INHBA-2884HTag:N/A
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human Activin A
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Cat.#:INHBA-461HTag:His
Source (Host):HEK293FSpecies:Human
Product nameRecombinant Human INHBA protein, His-tagged
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Cat.#:INHBA-5059HTag:His
Source (Host):Nicotiana benthamianaSpecies:Human
Product nameRecombinant Human Inhibin, Beta A, His-tagged
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Cat.#:INHBA-525HTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human INHBA
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Cat.#:INHBA-64HTag:
Source (Host):YeastSpecies:Human
Product nameRecombinant Human INHBA
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Cat.#:INHBA-761HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human INHBA, His tagged
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Cat.#:INHBA-955HTag:
Source (Host):Hi-5 insect cellsSpecies:Human
Product nameRecombinant Human INHBA Protein
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Cat.#:Inhba-248MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Inhba protein, His-tagged
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Cat.#:Inhba-4069MTag:His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Inhba, His tagged
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Cat.#:Inhba-249RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Inhba protein, His-tagged
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Cat.#:INHBA-3065RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat INHBA Protein
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Cat.#:Inhba-7805RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Inhba protein, His-tagged
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Cat.#:INHBA-6947CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken INHBA
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Cat.#:INHBA-7803CTag:His
Source (Host):E. coliSpecies:Chicken
Product nameRecombinant Chicken INHBA protein, His-tagged
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Cat.#:INHBA-7801CTag:His
Source (Host):E. coliSpecies:Cattle
Product nameRecombinant Cattle INHBA protein, His-tagged
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Cat.#:INHBA-7802HTag:His
Source (Host):E. coliSpecies:Horse
Product nameRecombinant Horse INHBA protein, His-tagged
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Cat.#:INHBA-7804PTag:His
Source (Host):E. coliSpecies:Pig
Product nameRecombinant Pig INHBA protein, His-tagged
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Cat.#:INHBA-5266HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Inhibin, Beta A, His-tagged
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Cat.#:INHBA-2078MCLTag:
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse INHBA cell lysate
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Cat.#:INHBA-114HGTag:
Source (Host):CHO cellSpecies:Human
Product nameGMP Recombinant Human INHBA Protein
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Cat.#:INHBA-111HTag:
Source (Host):Species:Human
Product nameRecombinant Human Activin A Reference standard
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Cat.#:INHBA-160HTag:
Source (Host):Species:Human
Product nameHuman Inhibin B Reference standard
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Involved Pathway

INHBA involved in several pathways and played different roles in them. We selected most pathways INHBA participated on our site, such as Cytokine-cytokine receptor interaction, TGF-beta signaling pathway, Signaling pathways regulating pluripotency of stem cells, which may be useful for your reference. Also, other proteins which involved in the same pathway with INHBA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cytokine-cytokine receptor interaction
CXCL11; IL12A; LTBR; CCL17; IL13RA1; EDAR; TNFSF4; Ifna15; EPO; CCL21B
TGF-beta signaling pathway
SP1; MAPK1; SMAD4; ZFYVE9; INHBA; SMAD6; TGFB2; BMP7A; FSTA; ACVR1C
Signaling pathways regulating pluripotency of stem cells
FZD6; WNT5A; FGFR2; INHBC; NODAL; ACVR1; LHX5; MAP2K2; SMAD2; WNT6

Protein Function

INHBA has several biochemical functions, for example, cytokine activity, growth factor activity, hormone activity. Some of the functions are cooperated with other proteins, some of the functions could acted by INHBA itself. We selected most functions INHBA had, and list some proteins which have the same functions with INHBA. You can find most of the proteins on our site.
Function
Related Protein
Function cytokine activity
Related Protein GDF11; IL13; EDN1; IL16; Il2; INHBB; Ctf2; IFNA4; Il1f6; IL11
Function growth factor activity
Related Protein NTF4; EFEMP1; LEP; BMP8B; VEGFAA; TGFB3; Il2; PDGFB; MSTNB; FGF12B
Function hormone activity
Related Protein INHBA; INHBAB; CSH1; EDN1; RETN; CHGB; GCGB; INS1; GH2; GNRH2
Function identical protein binding
Related Protein VPS41; PSME3; SOD1; FGFR1; SHMT2; ALCAMA; CLDN14; PLN; APOE; BAX
Function inhibin binding
Related Protein IGSF1; INHBA; ACVR1B; ACVR2A; INHA
Function peptide hormone binding
Related Protein PTH1R; CRHR2; MAS1; AGTR2; MC4R; NPR3; ACVR1; GHSR; MC3R; SLC40A1
Function protein binding
Related Protein BBS9; PPP1R13L; JAK2; TBK1; TEX10; XIAP; FAM108A1; CFL2; TESK2; SH2D3C
Function protein heterodimerization activity
Related Protein BIRC5; ADORA2A; KHDRBS2; INHA; ITGA3; H3F3B.1; ALX1; TOP2B; HIST1H2BA; PDGFA
Function transforming growth factor beta receptor binding
Related Protein NODAL; BMP8B; INHBB; GDF7; INHBAA; FKBP1A; TGFBR3; INHBC; GDF5; TGFB2
Function type II activin receptor binding
Related Protein INHBA; MAGI2

Interacting Protein

INHBA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with INHBA here. Most of them are supplied by our site. Hope this information will be useful for your research of INHBA.
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