Active Recombinant Human/Mouse/Rat INHBA Protein (Gly311-Ser426), GMP Grade
Cat.No. : | INHBA-09HG |
Product Overview : | GMP recombinant human/Mouse/Rat Activin A protein (Gly311-Ser426) without tag was expressed in Chinese Hamster Ovary cell line and manufactured and tested under cGMP guidelines. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate a subunit of the dimeric activin and inhibin protein complexes. These complexes activate and inhibit, respectively, follicle stimulating hormone secretion from the pituitary gland. The encoded protein also plays a role in eye, tooth and testis development. Elevated expression of this gene may be associated with cancer cachexia in human patients. |
Source : | CHO |
Species : | Human/Mouse/Rat |
Form : | Disulfide-linked homodimer |
Bio-activity : | Measured by its ability to induce hemoglobin expression in K562 human chronic myelogenous leukemia cells. The ED50 for this effect is 0.2-1.2 ng/mL. The specific activity of Recombinant Human/Mouse/Rat Activin A is >1000 units/mg, which is calibrated against the human Activin A WHO reference standard. |
Molecular Mass : | Predicted Molecular Mass: 13 kDa (monomer) SDS-PAGE: 14 kDa, reducing conditions; 24 kDa, non-reducing conditions |
Protein Length : | Gly311-Ser426 |
N-terminal Sequence Analysis : | Gly311-Leu-Glu-(Cys)-Asp-Gly-Lys-Val-Asn-Ile |
Endotoxin : | <0.10 EU/ μg of the protein by the LAL method. |
Purity : | >97%, by SDS-PAGE with silver staining. |
Storage : | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. A minimum of 12 months when stored at ≤ -20 centigrade as supplied. Refer to lot specific COA for the Use by Date. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, ≤ -20 centigrade under sterile conditions after reconstitution. |
Storage Buffer : | Lyophilized from a 0.2 μm filtered solution in Acetonitrile and TFA. |
Reconstitution : | Reconstitute at 100-500 μg/mL in sterile 4 mM HCl. |
Shipping : | The product is shipped with polar packs. |
Gene Name : | INHBA inhibin, beta A [ Homo sapiens ] |
Official Symbol : | INHBA |
Synonyms : | INHBA; inhibin, beta A; inhibin, beta A (activin A, activin AB alpha polypeptide); inhibin beta A chain; Inhibin, beta-1; activin beta-A chain; FSH-releasing protein; erythroid differentiation factor; erythroid differentiation protein; follicle-stimulating hormone-releasing protein; EDF; FRP; |
Gene ID : | 3624 |
mRNA Refseq : | NM_002192 |
Protein Refseq : | NP_002183 |
MIM : | 147290 |
UniProt ID : | P08476 |
Products Types
◆ Recombinant Protein | ||
INHBA-2404H | Recombinant Human INHBA Protein, MYC/DDK-tagged | +Inquiry |
INHBA-195H | Active Recombinant Human/Mouse/Rat INHBA Protein | +Inquiry |
INHBA-184H | Active Recombinant Human INHBA Protein (Gly311-Ser426), Animal-free, Carrier-free | +Inquiry |
Inhba-01M | Active Recombinant Mouse Inhba Protein | +Inquiry |
INHBA-196H | Active Recombinant Human/Mouse/Rat INHBA Protein | +Inquiry |
◆ Lysates | ||
INHBA-2078MCL | Recombinant Mouse INHBA cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket