kat2b
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  • Official Full Name
  • K(lysine) acetyltransferase 2B
  • Background
  • p300/CBP-associated factor (PCAF), also known as lysine acetyl-transferase 2B (KAT2B), is a transcriptional adaptor protein and histone acetyl-transferase (HAT) that functions as the catalytic subunit of the PCAF transcriptional co-activator complex (1).
  • Synonyms
  • KAT2B; K(lysine) acetyltransferase 2B; p300/CBP associated factor , PCAF; histone acetyltransferase KAT2B; GCN5; GCN5L; P/CAF; histone acetylase PCAF; CREBBP-associated factor; p300/CBP-associated factor; lysine acetyltransferase 2B; histone acetyltransfe
Cat.#:KAT2B-152HTag:His
Source (Host):Insect cellsSpecies:Human
Product nameRecombinant Human KAT2B Protein, His-tagged
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Cat.#:KAT2B-1654HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human K (lysine) Acetyltransferase 2B
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Cat.#:KAT2B-1081HTag:N/A
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human K (lysine) Acetyltransferase 2B
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Cat.#:KAT2B-122HTag:GST
Source (Host):E.coliSpecies:Human
Product nameRecombinant Human KAT2B Protein, GST-tagged
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Cat.#:KAT2B-123HTag:His
Source (Host):E.coliSpecies:Human
Product nameRecombinant Human KAT2B Protein, His-tagged
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Cat.#:KAT2B-124HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human KAT2B protein, GST-tagged
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Cat.#:KAT2B-125HTag:DDK
Source (Host):Insect cellsSpecies:Human
Product nameRecombinant Human KAT2B protein, DDK-tagged
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Cat.#:KAT2B-126HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human KAT2B protein, MYC/DDK-tagged
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Cat.#:KAT2B-1481HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human K(lysine) Acetyltransferase 2B, GST-tagged
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Cat.#:KAT2B-163HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human KAT2B, GST-tagged
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Cat.#:KAT2B-6953HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human KAT2B , GST-tagged
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Cat.#:KAT2B-8483HTag:His
Source (Host):Sf 21 Insect cellsSpecies:Human
Product nameRecombinant Human KAT2B, His-tagged
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Cat.#:Kat2b-177MTag:His
Source (Host):Sf 21 Insect cellsSpecies:Mouse
Product nameRecombinant Mouse K(lysine) Acetyltransferase 2B, His-tagged
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Cat.#:Kat2b-455MTag:His
Source (Host):Baculovirus-Insect CellsSpecies:Mouse
Product nameRecombinant Mouse Kat2b, His-tagged
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Cat.#:KAT2B-4103ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish KAT2B
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Involved Pathway

KAT2B involved in several pathways and played different roles in them. We selected most pathways KAT2B participated on our site, such as Notch signaling pathway, Thyroid hormone signaling pathway, HTLV-I infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with KAT2B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Notch signaling pathway
DTX3; DVL3A; RFNG; MFNG; DVL1B; JAG2B; MAML1; MFAP5; DLL3; ADAM17
Thyroid hormone signaling pathway
NRAS; PRKACG; RXRB; PIK3R1; NOTCH2; ATP1B2; SLC9A1; PIK3CD; MED30; PRKACA
HTLV-I infection
WNT6; RELB; GSK3B; HLA-DRB3; IKBKB; NFKB2; STAT5B; WNT7B; CCNB2; SLC25A4
Viral carcinogenesis
HIST1H4H; HIST1H4C; HIST1H2BJ; GRB2; HIST1H4K; GTF2A2; PIK3CG; YWHAG; PIK3R1; YWHAB

Protein Function

KAT2B has several biochemical functions, for example, RNA polymerase II regulatory region sequence-specific DNA binding, acetyltransferase activity, chromatin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KAT2B itself. We selected most functions KAT2B had, and list some proteins which have the same functions with KAT2B. You can find most of the proteins on our site.
Function
Related Protein
Function RNA polymerase II regulatory region sequence-specific DNA binding
Related Protein PURB; DLX2; BHLHA15; RXRG; PCGF6; EOMES; DMRT2; GFI1AA; RXRB; TFAP2D
Function acetyltransferase activity
Related Protein EP300; LPCAT3; Nat3; CREBBP; MBOAT4; ACNAT2; AANAT1; AANAT2; NAT14; KAT8
Function chromatin binding
Related Protein RERE; RAD51; MEF2A; MEN1; PBX2; FOS; BAP1; KDM6B; TCF7L2; GM606
Function cyclin-dependent protein serine/threonine kinase inhibitor activity
Related Protein CDKN2B; HEXIM2; CDKN1C; CDKN2D; CDKN2C; CDKN1A; Casp3; KAT2B; INCA1; CDKN1B
Function histone acetyltransferase activity
Related Protein KAT7A; NCOA1; NCOA2; NCOA3; KAT6B; MGEA5; KAT7; vnc; CLOCK; TAF1
Function histone acetyltransferase binding
Related Protein EID1; TP53; MTF1; PAX6; CEBPB; GLI3; KAT2B; FOXP3; ETS1; CITED2
Function histone deacetylase binding
Related Protein WDTC1; PKN1; TOP2B; HDAC10; BRMS1L; CAMTA2; NIPBL; KPNA2; HDAC1; TOP2A
Function lysine N-acetyltransferase activity, acting on acetyl phosphate as donor
Related Protein KAT2B; EP300; NAT8; NAT8B; RHBDL1; CEACAM21; ESCO2
Function protein binding
Related Protein STXBP1; RBKS; RASSF3; WAS; ADPRH; GRB7; RUNX1T1; TEF; RNF13; RDBP
Function protein complex binding
Related Protein ATM; SLC25A3; IST1; Casp3; VAMP2; NDUFA8; KLHL8; TULP3; MYC; RPH3A
Function protein kinase binding
Related Protein CRY1; RNF138; MAP3K13; NIPAL1; PKD1; PTPRJ; BCL2L14; PDGFRB; GDF3; NEFH
Function transcription coactivator activity
Related Protein SMARCB1; COPS5; KAT5; KMT2E; NFKBIB; YAP1; CITED4; NCOA3; MTF1; LPIN3
Function transcription cofactor activity
Related Protein MAX; AIRE; CREB1; IRF3; LDB1A; LDB2; PSMC5; MED16; NMI; PRKCBP1L
Function transcription factor binding
Related Protein ARNT; STK4; CDK9; YWHAZ; ETS1; HAND1; SOX8; CREG1; PDX1; TRP53

Interacting Protein

KAT2B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KAT2B here. Most of them are supplied by our site. Hope this information will be useful for your research of KAT2B.
BUB1B; E7; p03255-2