kat2b
Share
  • Official Full Name
  • K(lysine) acetyltransferase 2B
  • Background
  • p300/CBP-associated factor (PCAF), also known as lysine acetyl-transferase 2B (KAT2B), is a transcriptional adaptor protein and histone acetyl-transferase (HAT) that functions as the catalytic subunit of the PCAF transcriptional co-activator complex (1).
  • Synonyms
  • KAT2B; K(lysine) acetyltransferase 2B; p300/CBP associated factor , PCAF; histone acetyltransferase KAT2B; GCN5; GCN5L; P/CAF; histone acetylase PCAF; CREBBP-associated factor; p300/CBP-associated factor; lysine acetyltransferase 2B; histone acetyltransfe
Cat.#:KAT2B-152HTag:His
Source (Host):Insect cellsSpecies:Human
Product nameRecombinant Human KAT2B Protein, His-tagged
+Inquiry
Cat.#:KAT2B-1654HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human K (lysine) Acetyltransferase 2B
+Inquiry
Cat.#:KAT2B-1081HTag:N/A
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human K (lysine) Acetyltransferase 2B
+Inquiry
Cat.#:KAT2B-122HTag:GST
Source (Host):E.coliSpecies:Human
Product nameRecombinant Human KAT2B Protein, GST-tagged
+Inquiry
Cat.#:KAT2B-123HTag:His
Source (Host):E.coliSpecies:Human
Product nameRecombinant Human KAT2B Protein, His-tagged
+Inquiry
Cat.#:KAT2B-124HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human KAT2B protein, GST-tagged
+Inquiry
Cat.#:KAT2B-125HTag:DDK
Source (Host):Insect cellsSpecies:Human
Product nameRecombinant Human KAT2B protein, DDK-tagged
+Inquiry
Cat.#:KAT2B-126HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human KAT2B protein, MYC/DDK-tagged
+Inquiry
Cat.#:KAT2B-1481HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human K(lysine) Acetyltransferase 2B, GST-tagged
+Inquiry
Cat.#:KAT2B-163HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human KAT2B, GST-tagged
+Inquiry
Cat.#:KAT2B-6953HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human KAT2B , GST-tagged
+Inquiry
Cat.#:KAT2B-8483HTag:His
Source (Host):Sf 21 Insect cellsSpecies:Human
Product nameRecombinant Human KAT2B, His-tagged
+Inquiry
Cat.#:Kat2b-177MTag:His
Source (Host):Sf 21 Insect cellsSpecies:Mouse
Product nameRecombinant Mouse K(lysine) Acetyltransferase 2B, His-tagged
+Inquiry
Cat.#:Kat2b-455MTag:His
Source (Host):Baculovirus-Insect CellsSpecies:Mouse
Product nameRecombinant Mouse Kat2b, His-tagged
+Inquiry
Cat.#:KAT2B-4103ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish KAT2B
+Inquiry

Involved Pathway

KAT2B involved in several pathways and played different roles in them. We selected most pathways KAT2B participated on our site, such as Notch signaling pathway, Thyroid hormone signaling pathway, HTLV-I infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with KAT2B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Notch signaling pathway
DNER; DTX2; DLK1; RBPJL; RBPJB; KAT2B; NOTCH1; NUMBL; NCSTN; DLL1
Thyroid hormone signaling pathway
FOXO1; EP300; ATP2A2; ITGB3; MAP2K2; ITGAV; ATP1A1; CCND1; ESR1; SLC9A1
HTLV-I infection
HLA-DRA; HLA-DQA1; XIAP; CRTC3; Pdgfa&Pdgfb; WNT4; CRTC1; VCAM1; TGFB3; MAP3K14
Viral carcinogenesis
PIK3R2; BAK1; TRADD; BAX; PIK3CG; HIST1H4J; RBL2; CDC42; HIST1H2BB; HIST1H2BE

Protein Function

KAT2B has several biochemical functions, for example, RNA polymerase II regulatory region sequence-specific DNA binding, acetyltransferase activity, chromatin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KAT2B itself. We selected most functions KAT2B had, and list some proteins which have the same functions with KAT2B. You can find most of the proteins on our site.
Function
Related Protein
Function RNA polymerase II regulatory region sequence-specific DNA binding
Related Protein PHF21A; ZNF812; ATF5A; ARID5B; NHLH2; SNAI1; ALX1; TRP53; ZNF561; BHLHA15
Function acetyltransferase activity
Related Protein AANAT1; Nat3; HHAT; KAT6B; MBOAT1; CML5; NAT14; EP300; AANAT2; LPCAT3
Function chromatin binding
Related Protein SIX1; KDM5A; RDBP; TRP63; CDC45; NOC2L; ZFP143; TBL1Y; KDM8; CBX4
Function cyclin-dependent protein serine/threonine kinase inhibitor activity
Related Protein CDKN1BA; Casp3; CDKN2D; CDKN1B; CDKN2C; CDKN1C; KAT2B; CDKN2A; CDKN1D; HEXIM2
Function histone acetyltransferase activity
Related Protein HTATIP; NCOA2; KAT2B; TAF1L; NCOA1; EP300; HAT1; CDYL; MGEA5; vnc
Function histone acetyltransferase binding
Related Protein TRIM68; ZBTB7A; KAT2B; PCNA; CEBPB; CITED2; EPAS1; EID1; SIRT2; FOXP3
Function histone deacetylase binding
Related Protein HIF1A; YWHAE; MAGEA2B; HDAC10; HEY2; PKN2; NACC2; NCOR2; CEBPA; RFXANK
Function lysine N-acetyltransferase activity, acting on acetyl phosphate as donor
Related Protein NAT8B; RHBDL1; ESCO2; CEACAM21; EP300; KAT2B; NAT8
Function protein binding
Related Protein PRKD1; ZNF843; CXCR2; ZNF26; ELL; PARL; EXOC7; INHBA; DRAM1; DOCK4
Function protein complex binding
Related Protein CRTAP; EPHB1; MAPK8IP2; SH2B3; CDK5RAP2; TELO2; KCTD5; GNB2; SKIL; ABI1
Function protein kinase binding
Related Protein CAV1; TP53; TCTN2; DNM1; PAK2; CACNB2; RHOD; ZFP36; FGF19; FAM83A
Function transcription coactivator activity
Related Protein CCNE1; MYCBP; MED16; COPS5; ARL2BP; SOX10; USP16; TFAP2A; GMEB2; JUNBA
Function transcription cofactor activity
Related Protein ZFP667; TRIP13; ZNF763; NRG1; TFDP2; ZFP865; TMF1; ZFP710; PHF21B; LDB2B
Function transcription factor binding
Related Protein PURB; SOST; VDRA; BCL2; Trl; PARD6A; CD34; EP300; PPARGC1A; KLF5

Interacting Protein

KAT2B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KAT2B here. Most of them are supplied by our site. Hope this information will be useful for your research of KAT2B.
BUB1B; E7; p03255-2