Recombinant Human KAT2B Protein, His-tagged

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Recombinant Human KAT2B Protein, His-tagged

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Cat.No. : KAT2B-152H
Product Overview : Recombinant Human KAT2B fused with His tag was produced in Insect cells.
Description : CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation.
Source : Insect cells
Species : Human
Tag : His
Form : 50mMTris-HCl, pH 8.0, 250mMNaCl
Molecular Mass : ~100KDa
AA sequence : MSEAGGAGPGGCGAG AGAGAGPGALPPQPA ALPPAPPQGSPCAAA AGGSGACGPATAVAA AGTAEGPGGGGSARI AVKKAQLRSAPRAKK LEKLGVYSACKAEES CKCNGWKNPNPSPTP PRADLQQIIVSLTES CRSCSHALAAHVSHL ENVSEEEMNRLLGIV LDVEYLFTCVHKEED ADTKQVYFYLFKLLR KSILQRGKPVVEGSL EKKPPFEKPSIEQGV NNFVQYKFSHLPAKE RQTIVELAKMFLNRI NYWHLEAPSQRRLRS PNDDISGYKENYTRW LCYCNVPQFCDSLPR YETTQVFGRTLLRSV FTVMRRQLLEQARQE KDKLPLEKRTLILTH FPKFLSMLEEEVYSQ NSPIWDQDFLSASSR TSQLGIQTVINPPPV AGTISYNSTSSSLEQ PNAGSSSPACKASSG LEANPGEKRKMTDSH VLEEAKKPRVMGDIP MELINEVMSTITDPA AMLGPETNFLSAHSA RDEAARLEERRGVIE FHVVGNSLNQKPNKK ILMWLVGLQNVFSHQ LPRMPKEYITRLVFD PKHKTLALIKDGRVI GGICFRMFPSQGFTE IVFCAVTSNEQVKGY GTHLMNHLKEYHIKH DILNFLTYADEYAIG YFKKQGFSKEIKIPK TKYVGYIKDYEGATL MGCELNPRIPYTEFS VIIKKQKEIIKKLIE RKQAQIRKVYPGLSC FKDGVRQIPIESIPG IRETGWKPSGKEKSK EPRDPDQLYSTLKSI LQQVKSHQSAWPFME PVKRTEAPGYYEVIR FPMDLKTMSERLKNR YYVSKKLFMADLQRV FTNCKEYNPPESEYY KCANILEKFFFSKIK EAGLIDK
Purity : >90% as determined by SDS-PAGE
Storage : Short Term Storage at +4 centigrade, Long Term Storage at -20 centigrade to -80 centigrade. Avoid freeze/thaw cycles.
Figure :

Gene Name : KAT2B K(lysine) acetyltransferase 2B [ Homo sapiens ]
Official Symbol : KAT2B
Synonyms : KAT2B; K(lysine) acetyltransferase 2B; p300/CBP associated factor , PCAF; histone acetyltransferase KAT2B; GCN5; GCN5L; P/CAF; histone acetylase PCAF; CREBBP-associated factor; p300/CBP-associated factor; lysine acetyltransferase 2B; histone acetyltransferase PCAF; P; CAF; PCAF;
Gene ID : 8850
mRNA Refseq : NM_003884
Protein Refseq : NP_003875
MIM : 602303
UniProt ID : Q92831

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