KLK3 Protein, kallikrein-related peptidase 3

KLK3

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KLK3

Official Full Name kallikrein-related peptidase 3
Background Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Synonyms KLK3; kallikrein-related peptidase 3; APS; PSA; hK3; KLK2A1; prostate-specific antigen; seminin; P-30 antigen; kallikrein-3; semenogelase; gamma-seminoprotein; prostate specific antigen
    • Species :
    • Human
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • Human Cell
    • Human Semen
    • Human Seminal Fluid
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human KLK3-89H Recombinant Human KLK3 protein E.coli N/A
    Human KLK3-1536H Human Kallikrein-Related Peptidase 3 Human seminal fluid N/A
    Human KLK3-1832HCL Recombinant Human KLK3 cell lysate Human Cell N/A
    Human KLK3-385H Native Human Prostate Specific Antigen (PSA), High pI Isoform (IEF) Human Seminal Fluid N/A
    Human KLK3-386H Native Human Prostate Specific Antigen Human Semen N/A
    Human KLK3-387H Native Human Prostate Specific Antigen (PSA), Low pI Isoform (IEF) Human Seminal Fluid N/A
    Human KLK3-3H Prostate specific antigen (PSA) Reference Standard N/A
    Human KLK3-4937H Recombinant Human KLK3 Protein, GST-tagged Wheat Germ GST
    Human KLK3-6791H Recombinant Human Kallikrein-related Peptidase 3, His-tagged E.coli His
    Human KLK3-691H Recombinant Human KLK3 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human KLK3-6969H Recombinant Human KLK3, His tagged Human Cell His
    Human KLK3-8247H Native Human Prostate Specific Antigen Human Seminal Fluid N/A
    Human KLK3-8248H Native Human Prostate Specific Antigen Human Seminal fluid N/A
    Human KLK3-917H Recombinant Human KLK3 Protein, His-tagged HEK293 His
    Human PSA-01H Native Human PSA Human Seminal Fluid N/A
    Rhesus Macaque KLK3-2432R Recombinant Rhesus monkey KLK3 Protein, His-tagged Mammalian Cell His

    KLK3 involved in several pathways and played different roles in them. We selected most pathways KLK3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with KLK3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    KLK3 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by KLK3 itself. We selected most functions KLK3 had, and list some proteins which have the same functions with KLK3. You can find most of the proteins on our site.

    Function Related Protein

    KLK3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KLK3 here. Most of them are supplied by our site. Hope this information will be useful for your research of KLK3.

    Korbakis, D; Prassas, I; et al. Delineating monoclonal antibody specificity by mass spectrometry. JOURNAL OF PROTEOMICS 114:115-124(2015).
    Guzvic, M; Braun, B; et al. Combined Genome and Transcriptome Analysis of Single Disseminated Cancer Cells from Bone Marrow of Prostate Cancer Patients Reveals Unexpected Transcriptomes. CANCER RESEARCH 74:7383-7394(2014).

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