|Official Full Name||killer cell lectin-like receptor subfamily B, member 1|
|Background||Natural killer (NK) cells are lymphocytes that mediate cytotoxicity and secrete cytokines after immune stimulation. Several genes of the C-type lectin superfamily, including the rodent NKRP1 family of glycoproteins, are expressed by NK cells and may be involved in the regulation of NK cell function. The KLRB1 protein contains an extracellular domain with several motifs characteristic of C-type lectins, a transmembrane domain, and a cytoplasmic domain. The KLRB1 protein is classified as a type II membrane protein because it has an external C terminus. [provided by RefSeq, Jul 2008]|
|Synonyms||KLRB1; killer cell lectin-like receptor subfamily B, member 1; NKR; CD161; CLEC5B; NKR-P1; NKRP1A; NKR-P1A; hNKR-P1A; killer cell lectin-like receptor subfamily B member 1; C-type lectin domain family 5 member B; natural killer cell surface protein P1A;|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
KLRB1 involved in several pathways and played different roles in them. We selected most pathways KLRB1 participated on our site, such as Malaria, which may be useful for your reference. Also, other proteins which involved in the same pathway with KLRB1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Malaria||SDC2; LRP1; CD40; IL-8; HBA1; IL12A; VCAM1; SELP; HBA2; THBS4|
KLRB1 has several biochemical functions, for example, carbohydrate binding, transmembrane signaling receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by KLRB1 itself. We selected most functions KLRB1 had, and list some proteins which have the same functions with KLRB1. You can find most of the proteins on our site.
|carbohydrate binding||ZG16B; PVRL1; CLEC6A; OS9; GALNTL4; LGALS2A; GALNT6; LGALSLB; GANAB; KLRA8|
|transmembrane signaling receptor activity||IL4R.1; TLR10; LILRA1; CLDN3; TLR2-1; PTH1RA; KIR2DL4; LILRB3; CD69; LGR6|
KLRB1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KLRB1 here. Most of them are supplied by our site. Hope this information will be useful for your research of KLRB1.