KLRB1 Protein, killer cell lectin-like receptor subfamily B, member 1


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Official Full Name killer cell lectin-like receptor subfamily B, member 1
Background Natural killer (NK) cells are lymphocytes that mediate cytotoxicity and secrete cytokines after immune stimulation. Several genes of the C-type lectin superfamily, including the rodent NKRP1 family of glycoproteins, are expressed by NK cells and may be involved in the regulation of NK cell function. The KLRB1 protein contains an extracellular domain with several motifs characteristic of C-type lectins, a transmembrane domain, and a cytoplasmic domain. The KLRB1 protein is classified as a type II membrane protein because it has an external C terminus. [provided by RefSeq, Jul 2008]
Synonyms KLRB1; killer cell lectin-like receptor subfamily B, member 1; NKR; CD161; CLEC5B; NKR-P1; NKRP1A; NKR-P1A; hNKR-P1A; killer cell lectin-like receptor subfamily B member 1; C-type lectin domain family 5 member B; natural killer cell surface protein P1A;
    • Species :
    • Human
    • Mouse
    • Rat
    • Rhesus monkey
    • Source :
    • E.coli
    • HEK293
    • Insect Cell
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • HIgG
    • T7
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human KLRB1-228H Recombinant Human KLRB1 Protein, hIgG-His-tagged Insect Cell His/HIgG
    Human KLRB1-4896HCL Recombinant Human KLRB1 293 Cell Lysate HEK293 N/A
    Human KLRB1-4918H Recombinant Human KLRB1 Protein, GST-tagged Wheat Germ GST
    Human KLRB1-4919H Recombinant Human KLRB1 Protein, His-tagged E.coli His
    Human KLRB1-5701H Recombinant Human KLRB1 protein, His & T7-tagged E.coli His/T7
    Mouse KLRB1-8777M Recombinant Mouse KLRB1 Protein Mammalian Cell His
    Rat KLRB1-3295R Recombinant Rat KLRB1 Protein Mammalian Cell His
    Rhesus monkey KLRB1-1588R Recombinant Rhesus Monkey KLRB1 Protein HEK293 N/A

    KLRB1 involved in several pathways and played different roles in them. We selected most pathways KLRB1 participated on our site, such as Malaria, which may be useful for your reference. Also, other proteins which involved in the same pathway with KLRB1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Malaria SDC2; LRP1; CD40; IL-8; HBA1; IL12A; VCAM1; SELP; HBA2; THBS4

    KLRB1 has several biochemical functions, for example, carbohydrate binding, transmembrane signaling receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by KLRB1 itself. We selected most functions KLRB1 had, and list some proteins which have the same functions with KLRB1. You can find most of the proteins on our site.

    Function Related Protein
    carbohydrate binding ZG16B; PVRL1; CLEC6A; OS9; GALNTL4; LGALS2A; GALNT6; LGALSLB; GANAB; KLRA8
    transmembrane signaling receptor activity IL4R.1; TLR10; LILRA1; CLDN3; TLR2-1; PTH1RA; KIR2DL4; LILRB3; CD69; LGR6

    KLRB1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KLRB1 here. Most of them are supplied by our site. Hope this information will be useful for your research of KLRB1.


    Hoffmann, J; Shmeleva, EV; et al. Myocardial Ischemia and Reperfusion Leads to Transient CD8 Immune Deficiency and Accelerated Immunosenescence in CMV-Seropositive Patients. CIRCULATION RESEARCH 116:87-U222(2015).
    Shimizu, K; Sato, Y; et al. KLRG(+) invariant natural killer T cells are long-lived effectors. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 111:12474-12479(2014).

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