Recombinant Human KLRB1 protein, His & T7-tagged

• Cat.No.: KLRB1-5701H
• Product Overview: Recombinant Human KLRB1 aa. (Lys73~Ser188 (Accession # Q12918)) fused with N-terminal His & T7 tag was produced in E. coli cells.

Specification

• Species: Human
• Source: E.coli
• Tag: His&T7
• Protein Length: Lys73~Ser188
• Description: Natural killer (NK) cells are lymphocytes that mediate cytotoxicity and secrete cytokines after immune stimulation. Several genes of the C-type lectin superfamily, including the rodent NKRP1 family of glycoproteins, are expressed by NK cells and may be involved in the regulation of NK cell function. The KLRB1 protein contains an extracellular domain with several motifs characteristic of C-type lectins, a transmembrane domain, and a cytoplasmic domain. The KLRB1 protein is classified as a type II membrane protein because it has an external C terminus.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 17.3kDa
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 8.4.
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% sucrose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: KLRB1 killer cell lectin like receptor B1 [ Homo sapiens (human) ]
• Official Symbol: KLRB1
• Synonyms: KLRB1; killer cell lectin like receptor B1; NKR; CD161; CLEC5B; NKR-P1; NKRP1A; NKR-P1A; hNKR-P1A; killer cell lectin-like receptor subfamily B member 1; C-type lectin domain family 5 member B; killer cell lectin-like receptor subfamily B, member 1; natural killer cell surface protein P1A
• Gene ID: 3820
• mRNA Refseq: NM_002258.2
• Protein Refseq: NP_002249.1
• UniProt ID: Q12918