|Official Full Name||left-right determination factor 1|
|Background||This gene encodes a member of the TGF-beta family of proteins. A similar secreted protein in mouse plays a role in left-right asymmetry determination of organ systems during development. Alternative processing of this protein can yield three different products. This gene is closely linked to both a related family member and a related pseudogene. [provided by RefSeq, Jul 2008]|
|Synonyms||LEFTY1; left-right determination factor 1; LEFTB; LEFTYB; protein lefty-1; protein lefty-B; left-right determination factor B; left-right determination, factor B;|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
LEFTY1 involved in several pathways and played different roles in them. We selected most pathways LEFTY1 participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with LEFTY1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Developmental Biology||DCC; ARPC2; CLTA; TCF12; ACVR1C; EPHA4A; NRTN; POU5F3; MYOD1; CACNG2|
|Integrated Pancreatic Cancer Pathway||IL11; CASP12; MST1; FST; MAPK4; FKBP1B; PPP1R13L; AGA; CD82; RAPGEF3|
|Regulation of signaling by NODAL||TDGF1; LEFTY1; ACVR1C; CFC1|
|Signaling by NODAL||DRAP1; TDGF1; CFC1; FOXH1; PCSK6; GDF1; ACVR1C; LEFTY1|
|TGF Beta Signaling Pathway||ZNF423; FOXH1; NOG; ZFP423; RUNX3; FST; TGFBR3; LEFTY1; ENG|
|TGF-beta signaling pathway||BAMBIB; THBS1; ROCK1; GDF5; ID2B; NOG3; ACVR1BA; PPP2CA; ACVR1L; TGFBR1|
LEFTY1 has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by LEFTY1 itself. We selected most functions LEFTY1 had, and list some proteins which have the same functions with LEFTY1. You can find most of the proteins on our site.
|cytokine activity||GM13288; IFNA17; SPAW; FAM3B; IFNG1-2; CMTM2; GDF15; INHBB; GDF10B; IL1F10|
|growth factor activity||IGF2B; Fgf15; IL6; NRG4; FGF17; INHBE; CECR1A; PDGFB; EPGN; GH1|
|transforming growth factor beta receptor binding||INHBA; MSTNB; BMP8A; SMAD2; BMP15; INHBB; TGFBR3; BMP6; BMP4; GDF7|
LEFTY1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LEFTY1 here. Most of them are supplied by our site. Hope this information will be useful for your research of LEFTY1.