lefty1
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  • Official Full Name
  • left-right determination factor 1
  • Background
  • This gene encodes a member of the TGF-beta family of proteins. A similar secreted protein in mouse plays a role in left-right asymmetry determination of organ systems during development. Alternative processing of this protein can yield three different products. This gene is closely linked to both a related family member and a related pseudogene. [provided by RefSeq, Jul 2008]
  • Synonyms
  • LEFTY1; left-right determination factor 1; LEFTB; LEFTYB; protein lefty-1; protein lefty-B; left-right determination factor B; left-right determination, factor B;
Cat.#:LEFTY1-367HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human LEFTY1 Protein, His-tagged
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Cat.#:Lefty1-370MTag:His/GST
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Lefty1 Protein, His/GST-tagged
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Cat.#:Lefty1-371RTag:His/GST
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Lefty1 Protein, His/GST-tagged
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Cat.#:Lefty1-579MTag:N/A
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Left Right Determination Factor 1
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Cat.#:Lefty1-1915HTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human Left-right Determination Factor 1
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Cat.#:Lefty1-1765MTag:N/A
Source (Host):NS0Species:Mouse
Product nameRecombinant Mouse Left Right Determination Factor 1
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Cat.#:Lefty1-629MTag:
Source (Host):NSO CellsSpecies:Mouse
Product nameRecombinant Mouse Lefty1
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Cat.#:LEFTY1-9036MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse LEFTY1 Protein
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Cat.#:LEFTY1-980HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human LEFTY1 cell lysate
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Involved Pathway

LEFTY1 involved in several pathways and played different roles in them. We selected most pathways LEFTY1 participated on our site, such as Developmental Biology, Integrated Pancreatic Cancer Pathway, Regulation of signaling by NODAL, which may be useful for your reference. Also, other proteins which involved in the same pathway with LEFTY1 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Developmental Biology
GFRA1; LGI4; TCF4; GPC1B; SPRED3; DUSP5; RHOC; PRDM14; COL9A1B; COL4A5
Integrated Pancreatic Cancer Pathway
MYT1; BRF1; NOXA1; RAPGEF3; TOP2A; GPRC5A; FST; IL11; RB1CC1; MAPK4
Regulation of signaling by NODAL
TDGF1; LEFTY1; CFC1; ACVR1C
Signaling by NODAL
ACVR1C; DRAP1; GDF1; PCSK6; LEFTY1; FOXH1; TDGF1; CFC1
TGF Beta Signaling Pathway
RUNX3; ZFP423; TGFBR3; NOG; LEFTY1; FST; ZNF423; FOXH1; ENG
TGF-beta signaling pathway
RBL1; IFNG1-2; BMP5; TGFBR2; LFT1; FST; LEFTY1; CUL1; TGFBR1; SMAD1

Protein Function

LEFTY1 has several biochemical functions, for example, cytokine activity, growth factor activity, transforming growth factor beta receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LEFTY1 itself. We selected most functions LEFTY1 had, and list some proteins which have the same functions with LEFTY1. You can find most of the proteins on our site.
Function
Related Protein
Function cytokine activity
Related Protein IL17C; IL3; MSTN; IL17A/F3; WNT7A; BMP1; CCL38.1; SPP1; GDF6B; IFN-a
Function growth factor activity
Related Protein HBEGFB; VEGFAA; TGFB1A; IL7; EPGN; GDF1; BMP10; INHBE; TGFB3; FGF13
Function transforming growth factor beta receptor binding
Related Protein GDF7; BMP8B; MSTN; BMP7B; BMP4; SMAD2; BMP10; LFT1; BMP2; BMP5