LEFTY1

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LEFTY1

Official Full Name left-right determination factor 1
Background This gene encodes a member of the TGF-beta family of proteins. A similar secreted protein in mouse plays a role in left-right asymmetry determination of organ systems during development. Alternative processing of this protein can yield three different products. This gene is closely linked to both a related family member and a related pseudogene. [provided by RefSeq, Jul 2008]
Synonyms LEFTY1; left-right determination factor 1; LEFTB; LEFTYB; protein lefty-1; protein lefty-B; left-right determination factor B; left-right determination, factor B;
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • NS0
    • Tag :
    • His
    • GST
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human Lefty1-1915H Recombinant Human Left-right Determination Factor 1 HEK293 N/A
    Human LEFTY1-367H Recombinant Human LEFTY1 Protein, His-tagged E.coli His
    Human LEFTY1-980HCL Recombinant Human LEFTY1 cell lysate N/A
    Mouse Lefty1-1765M Recombinant Mouse Left Right Determination Factor 1 NS0 N/A
    Mouse Lefty1-370M Recombinant Mouse Lefty1 Protein, His/GST-tagged E.coli His/GST
    Mouse Lefty1-579M Recombinant Mouse Left Right Determination Factor 1 E.coli N/A
    Mouse Lefty1-629M Recombinant Mouse Lefty1 NS0 N/A
    Mouse LEFTY1-9036M Recombinant Mouse LEFTY1 Protein Mammalian Cell His
    Rat Lefty1-371R Recombinant Rat Lefty1 Protein, His/GST-tagged E.coli His/GST

    LEFTY1 involved in several pathways and played different roles in them. We selected most pathways LEFTY1 participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with LEFTY1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Developmental Biology DCC; ARPC2; CLTA; TCF12; ACVR1C; EPHA4A; NRTN; POU5F3; MYOD1; CACNG2
    Integrated Pancreatic Cancer Pathway IL11; CASP12; MST1; FST; MAPK4; FKBP1B; PPP1R13L; AGA; CD82; RAPGEF3
    Regulation of signaling by NODAL TDGF1; LEFTY1; ACVR1C; CFC1
    Signaling by NODAL DRAP1; TDGF1; CFC1; FOXH1; PCSK6; GDF1; ACVR1C; LEFTY1
    TGF Beta Signaling Pathway ZNF423; FOXH1; NOG; ZFP423; RUNX3; FST; TGFBR3; LEFTY1; ENG
    TGF-beta signaling pathway BAMBIB; THBS1; ROCK1; GDF5; ID2B; NOG3; ACVR1BA; PPP2CA; ACVR1L; TGFBR1

    LEFTY1 has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by LEFTY1 itself. We selected most functions LEFTY1 had, and list some proteins which have the same functions with LEFTY1. You can find most of the proteins on our site.

    Function Related Protein
    cytokine activity GM13288; IFNA17; SPAW; FAM3B; IFNG1-2; CMTM2; GDF15; INHBB; GDF10B; IL1F10
    growth factor activity IGF2B; Fgf15; IL6; NRG4; FGF17; INHBE; CECR1A; PDGFB; EPGN; GH1
    transforming growth factor beta receptor binding INHBA; MSTNB; BMP8A; SMAD2; BMP15; INHBB; TGFBR3; BMP6; BMP4; GDF7

    LEFTY1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LEFTY1 here. Most of them are supplied by our site. Hope this information will be useful for your research of LEFTY1.

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