Species : |
Cynomolgus |
Source : |
HEK293 |
Tag : |
His |
Description : |
Lefty (left-right determination factors) are a class of proteins that are closely related members of the TGF-beta superfamily of growth factors. These proteins are secreted and play a role in left-right asymmetry determination of organ systems during development.[1] Mutations of the genes encoding these proteins have been associated with left-right axis malformations, particularly in the heart and lungs. |
Molecular Mass : |
The protein has a calculated MW of 39.7 kDa. |
AA Sequence : |
LTGEQLLGSLLQQLQLSEAPVLDRADMEELVIPAHVRAQYVTLLQRSHGDRSRGKRFSQSFREVAGRFLASEASTHLLVFGMEQRLPPNSELVQAVLRLFQEPVPKATLHRHGRLSPRSARARVTVEWLRVRDDGSNRTSLIDSRLVSVHESGWKVFDVTEAVNFWQQLSRPRQPLLLQVSVQREHPGPLASGAHKLVRFASQGAPAGLGEPQLELHTLDLGDYGAQGDCDPEAPVTEGTRCCRQEMYIDLQGMKWADNWVLEPPGFLAYECVGTCQQPPEALAFKWPFLGPRQCIASETASLPMIVSIKEGGRTRPQVVSLPNMRVQKCSCASDGALVPRGLQPDDDDKHHHHHH |
Endotoxin : |
<1EU/ug by LAL |
Purity : |
>90% by SDS-PAGE |
Storage : |
Store it under sterile conditions at -20 to -80 ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Concentration : |
1.25 mg/ml |
Storage Buffer : |
25mM Tris, 150mM NaCl, pH 8.0. |