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Recombinant Human LEFTY1 Protein, Fc-tagged

Cat.No. : LEFTY1-003H
Product Overview : Recombinant Human LEFTY1 Protein with Fc tag was expressed in HEK293.
  • Specification
  • Gene Information
  • Related Products
Description : This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which plays a role in left-right asymmetry determination of organ systems during development. This gene is closely linked to both a related family member and a related pseudogene.
Source : HEK293
Species : Human
Tag : Fc
Molecular Mass : 59 kDa
AA Sequence : RFSQSFREVAGRFLALEASTHLLVF GMEQRLPPNSELVQAVLRLFQEPVP KAALHRHGRLSPRSARARVTVEWLR VRDDGSNRTSLIDSRLVSVHESGWK AFDVTEAVNFWQQLSRPRQPLLLQV SVQREHLGPLASGAHKLVRFASQGA PAGLGEPQLELHTLDLGDYGAQGDC DPEAPMTEGTRCCRQEMYIDLQGMK WAENWVLEPPGFLAYECVGTCRQPP EALAFKWPFLGPRQCIASETDSLPM IVSIKEGGRTRPQVVSLPNMRVQKC SCASDGALVPRRLQPDDDDKEPKSS DKTHTCPPCPAPELLGGPSVFLFPP KPKDTLMISRTPEVTCVVVDVSHED PEVKFNWYVDGVEVHNAKTKPREEQ YNSTYRVVSVLTVLHQDWLNGKEYK CKVSNKALPAPIEKTISKAKGQPRE PQVYTLPPSRDELTKNQVSLTCLVK GFYPSDIAVEWESNGQPENNYKTTP PVLDSDGSFFLYSKLTVDKSRWQQG NVFSCSVMHEALHNHYTQKSLSLSP GK
Endotoxin : < 1 EU/μg by LAL
Purity : > 70 % by SDS-PAGE
Storage : Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Concentration : 0.34 mg/mL
Storage Buffer : PBS, pH 7.4
Gene Name : LEFTY1 left-right determination factor 1 [ Homo sapiens (human) ]
Official Symbol : LEFTY1
Synonyms : LEFTY1; left-right determination factor 1; LEFTB; LEFTYB; left-right determination factor 1; left-right determination factor B; protein lefty-1; protein lefty-B
Gene ID : 10637
mRNA Refseq : NM_020997
Protein Refseq : NP_066277
MIM : 603037
UniProt ID : O75610

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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