Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

LILRB2

  • Official Full Name

    leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2

  • Overview

    This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.
  • Synonyms

    LILRB2; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2; leukocyte immunoglobulin-like receptor subfamily B member 2; CD85d; ILT4; LIR 2; LIR2; MIR 10; MIR10; ILT-4; Ig-like transcript 4; immunoglobulin-like transcript 4; CD85 antigen-like family member D; leukocyte immunoglobulin-like receptor 2; monocyte/macrophage immunoglobulin-like receptor 10; leukocyte immunoglobulin-like receptor subfamily B member 2 soluble isoform; eukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6; LIR-2; LILRA6; MIR-10;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Cynomolgus
  • Human
  • E.coli
  • HEK293
  • HEK293T
  • Human Cell
  • Human Cells
  • Mammalian cells
  • C
  • Avi
  • 6His
  • His
  • Fc
  • Fc Chimera
  • GST
  • hFc
  • His (Fc)
  • His(C
  • ter)
  • His\Avi
  • Myc
  • DDK
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human LILRB2-253H Active Recombinant Human LILRB2, Fc Chimera Mammalian cells Fc Chimera
Human LILRB2-115H Recombinant Human LILRB2, His-tagged HEK293 His
Human LILRB2-8639H Active Recombinant Human LILRB2 protein, His-tagged HEK293 His Gln22-Val461
Human LILRB2-391H Recombinant Human LILRB2 protein, Fc-tagged Human Cells Fc Gln22-His458
Human LILRB2-345H Active Recombinant Human LILRB2 protein, Fc-tagged HEK293 Fc Gln 22 - Val 461
Human LILRB2-581H Recombinant Human LILRB2, GST-tagged E.coli GST 24-350aa
Human LILRB2-1059HCL Recombinant Human LILRB2 cell lysate Human Cell N/A
Human LILRB2-1211HCL Recombinant Human LILRB2 cell lysate Human Cell N/A
Human LILRB2-647H Recombinant Human LILRB2 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human LILRB2-4474H Recombinant Human LILRB2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human LILRB2-423HB Recombinant Human LILRB2 protein, His-Avi-tagged, Biotinylated HEK293 His-Avi It contains Met1-Val461.
Human LILRB2-423H Recombinant Human LILRB2 protein, His-Avi-tagged HEK293 His-Avi Met1-Val461
Human LILRB2-116H Recombinant Human LILRB2 protein, Fc-Avi-tagged, Biotinylated HEK293 Fc-Avi Gln22-Val461
Human LILRB2-01H Recombinant Human LILRB2 Protein, His-tagged HEK293 His
Human LILRB2-8639HB Recombinant Human LILRB2 protein, His-tagged, Biotinylated HEK293 His
Human LILRB2-198H Recombinant Human LILRB2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human LILRB2-30H Recombinant Human LILRB2 Protein, C-Avi-6His tagged, Biotinylated Human Cell C-Avi-6His Gln22-His458
Human LILRB2-232H Recombinant Human LILRB2 Protein (ECD), His-tagged(C-ter) HEK293 His(C-ter) Gln22-Val461
Human LILRB2-419H Recombinant Human LILRB2 protein, hFc-tagged HEK293 hFc Gln22-Val460
Human LILRB2-3883H Recombinant Human LILRB2 Protein (Gln22-His458), C-His tagged Mammalian cells C-His Gln22-His458
Human LILRB2-355H Recombinant Human LILRB2 Protein, Fc-tagged HEK293 Fc 598
Human LILRB2-202H Recombinant Human LILRB2 Protein, His\Avi-tagged Human Cell His\Avi
Human LILRB2-198H-B Recombinant Human LILRB2 Protein Pre-coupled Magnetic Beads HEK293
Human LILRB2-3885H Recombinant Human LILRB2 Protein (Gln22-Val461), N-His tagged E.coli N-His Gln22-Val461
Human LILRB2-354H Recombinant Human LILRB2 Protein, His-tagged HEK293 His 598
Human LILRB2-0967H Recombinant Human LILRB2 Protein (Leu53-Val255), N-His tagged E.coli N-His Leu53-Val255
Human LILRB2-3882H Recombinant Human LILRB2 Protein (Met1-Val461), C-His tagged Mammalian cells C-His Met1-Val461
Cynomolgus LILRB2-2188C Recombinant Cynomolgus LILRB2 protein, His-tagged HEK293 His Gly 24 - Leu 448
Cynomolgus LILRB2-0359C Recombinant Cynomolgus LILRB2 protein, His-Avi-tagged, Biotinylated HEK293 His-Avi Gly24-Leu448
Cynomolgus LILRB2-01C Recombinant Cynomolgus LILRB2 Protein, Biotinylated HEK293 N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein

LILRB2 involved in several pathways and played different roles in them. We selected most pathways LILRB2 participated on our site, such as Adaptive Immune System, Immune System, Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell, which may be useful for your reference. Also, other proteins which involved in the same pathway with LILRB2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Adaptive Immune SystemMGC174857;UBE2J2;MAPKAP1;TREM1;PAG1;GM11711;CTSD;ERAP1;KLC3
Immune SystemNLRC5;PRLRB;S100B;TRIM63;TREML2;PANX1B;MICA;USP18;CTSO
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cellTREML4;SIGLEC8;LILRB2;LAIR1;CXADR;SIGLEC10;CD300E;OSCAR;KLRB1F
Osteoclast differentiationLILRB3;NOX3;MAPK3;STAT2;NCF2;TNFRSF11B;PPP3CA;PIK3R2;IFNGR2

LILRB2 has several biochemical functions, for example, MHC class I protein binding, MHC class Ib protein binding, cell adhesion molecule binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LILRB2 itself. We selected most functions LILRB2 had, and list some proteins which have the same functions with LILRB2. You can find most of the proteins on our site.

Function Related Protein
MHC class I protein bindingCD8B;LILRB2;Pilrb1;BCAP31;DERL1;TUBB4B;TUBB;CD8A;TAPBP
MHC class Ib protein bindingTAP1;LILRB2;TAP2
cell adhesion molecule bindingFGFR1;ITGA4;EZR;CADM4;CADM1B;POSTN;CD200;ITGAL;CD226
inhibitory MHC class I receptor activity
protein bindingVPS41;CFL2;SNAP91;PDLIM3;WDR18;ANKRD10;INCA1;TSPAN6;SNAP47
protein phosphatase 1 bindingSTAU1;PPP1R15A;KCNQ1;PHACTR3B;SH3RF2;FER;PHACTR1;TCTEX1D4;PAWR
receptor activityOPN1SW;TREM2;NLGN4Y;ERBB3B;ANTXR2;PVRL1B;ANTXRL;SLC40A1;OR3A2

LILRB2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LILRB2 here. Most of them are supplied by our site. Hope this information will be useful for your research of LILRB2.

metA; ppsA; pdaA

  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All LILRB2 Products

Required fields are marked with *

My Review for All LILRB2 Products

Required fields are marked with *

logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends