Recombinant Human LILRB2 Protein, His\Avi-tagged
Cat.No. : | LILRB2-202H |
Product Overview : | Recombinant Human Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 2 is produced by our Mammalian expression system and the target gene encoding Gln22-His458 is expressed with a Avi, 6His tag at the C-terminus. |
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Description : | Members of the immunoglobulin-like transcript (ILT) family are activating and inhibitory immunoreceptors whose genes are located same locus that encodes killer cell Ig-like receptors (KIR). Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 2 (LIR-2) is a type I transmembrane protein. LIR-2 is expressed primarily on monocytes and dendritic cells (DC). Human LIR-2 is produced as a 598 amino acino acid precursor including a 21 aa signal sequence, a 440 aa extracellular domain (ECD), a 21 aa transmenbrane segment, and a 116 aa cytoplasmic domain. LIR-2 binds to Classical MHCI proteins. Ligation of LIR-2 incluces Tyr phosphorylation within its cytoplasmic ITIMs, a requirement for association with SHP-1. LIR-2 mediates tolerogenic DC-induced CD4+ T cell energy in vitro and in vivo. |
Source : | Human Cells |
Species : | Human |
Tag : | His\Avi |
Form : | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. |
AA Sequence : | Gln22-His458 |
Endotoxin : | Less than 0.1 ng/ug (1 EU/ug). |
Shipping : | Ambient |
Gene Name : | LILRB2 leukocyte immunoglobulin like receptor B2 [ Homo sapiens (human) ] |
Official Symbol : | LILRB2 |
Synonyms : | Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 2; LIR-2; Leukocyte Immunoglobulin-Like Receptor 2; CD85 Antigen-Like Family Member D; Immunoglobulin-Like Transcript 4; Monocyte/Macrophage Immunoglobulin-Like Receptor 10; MIR-10; CD85d; LILRB2; ILT4; LIR2; MIR10; CD85D; ILT-4 |
Gene ID : | 10288 |
mRNA Refseq : | NM_001080978.4 |
Protein Refseq : | NP_001074447.2 |
MIM : | 604815 |
UniProt ID : | Q8N423 |
Products Types
◆ Recombinant Protein | ||
LILRB2-354H | Recombinant Human LILRB2 Protein, His-tagged | +Inquiry |
LILRB2-232H | Recombinant Human LILRB2 Protein (ECD), His-tagged(C-ter) | +Inquiry |
LILRB2-01H | Recombinant Human LILRB2 Protein, His-tagged | +Inquiry |
LILRB2-30H | Recombinant Human LILRB2 Protein, C-Avi-6His tagged, Biotinylated | +Inquiry |
LILRB2-355H | Recombinant Human LILRB2 Protein, Fc-tagged | +Inquiry |
◆ Lysates | ||
LILRB2-1211HCL | Recombinant Human LILRB2 cell lysate | +Inquiry |
LILRB2-1059HCL | Recombinant Human LILRB2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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