mmab
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  • Official Full Name
  • methylmalonic aciduria (cobalamin deficiency) cblB type
  • Background
  • This gene encodes a protein that catalyzes the final step in the conversion of vitamin B(12) into adenosylcobalamin (AdoCbl), a vitamin B12-containing coenzyme for methylmalonyl-CoA mutase. Mutations in the gene are the cause of vitamin B12-dependent methylmalonic aciduria linked to the cblB complementation group. Alternatively spliced transcript variants have been found.
  • Synonyms
  • MMAB; methylmalonic aciduria (cobalamin deficiency) cblB type; methylmalonic aciduria (cobalamin deficiency) type B; cob(I)yrinic acid a,c-diamide adenosyltransferase, mitochondrial; ATP:cob(I)alamin adenosyltransferase; cblB; mitochondrial; aquocob(I)alamin vitamin B12s adenosyltransferase; ATP:corrinoid adenosyltransferase; ATR; c-diamide adenosyltransferase; Cob; Cob(I)alamin adenosyltransferase; Cob(I)yrinic acid a; Methylmalonic aciduria type B protein; MGC20496; MMAB_HUMAN; OTTHUMP00000240563; OTTHUMP00000240564
Cat.#:MMAB-574HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human MMAB Protein, MYC/DDK-tagged
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Cat.#:MMAB-27647THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MMAB, His-tagged
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Cat.#:MMAB-629HTag:GST
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human MMAB, GST-tagged
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Cat.#:MMAB-630HTag:GST
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human MMAB, GST-tagged
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Cat.#:MMAB-9896MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse MMAB Protein
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Cat.#:MMAB-5218ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish MMAB
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Cat.#:MMAB-787HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MMAB, His-tagged
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Cat.#:MMAB-4285HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human MMAB 293 Cell Lysate
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Involved Pathway

MMAB involved in several pathways and played different roles in them. We selected most pathways MMAB participated on our site, such as Porphyrin and chlorophyll metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with MMAB were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Porphyrin and chlorophyll metabolism
BLVRA; COX10; CP; HCCSB; FXN; UGT1A9; UGT2B15; UGT1A4; UGT1A3; HMOX2A
Metabolic pathways
PTGS2; SDHD; ATP6V1C1A; PNPLA3; CSAD; TK2; NME2B.1; COX6A2; ZNRD1; POLR1C

Protein Function

MMAB has several biochemical functions, for example, ATP binding, cob(I)yrinic acid a,c-diamide adenosyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MMAB itself. We selected most functions MMAB had, and list some proteins which have the same functions with MMAB. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein RPS6KA3B; CCT8L2; TSSK4; ETNK1; MAPK3; MYH4; TTF2; TRAP1; STK30; SGK1
Function cob(I)yrinic acid a,c-diamide adenosyltransferase activity
Related Protein MMAB

Interacting Protein

MMAB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MMAB here. Most of them are supplied by our site. Hope this information will be useful for your research of MMAB.
ICT1

MMAB Related Articles

Carvalho, KC; Maia, BM; et al. Best practice for PTEN gene and protein assessment in anatomic pathology. ACTA HISTOCHEMICA 116:25-31(2014).
Kaneko, MK; Morita, S; et al. Establishment of novel monoclonal antibodies KMab-1 and MMab-1 specific for IDH2 mutations. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 432:40-45(2013).