myl4
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  • Official Full Name
  • myosin, light chain 4, alkali; atrial, embryonic
  • Background
  • Myosin is a hexameric ATPase cellular motor protein. It is composed of two myosin heavy chains, two nonphosphorylatable myosin alkali light chains, and two phosphorylatable myosin regulatory light chains. This gene encodes a myosin alkali light chain that is found in embryonic muscle and adult atria. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.
  • Synonyms
  • MYL4; myosin, light chain 4, alkali; atrial, embryonic; myosin, light polypeptide 4, alkali; myosin light chain 4; ALC1; AMLC; GT1; myosin; atrial/fetal muscle; light chain; PRO1957; embryonic muscle/atrial isoform; ALC 1; Atrial/embryonic alkali myosin light chain; GT 1; MLC 1; MLC1; MYL 4; MYL4_HUMAN; Myosin atrial/fetal muscle light chain; Myosin light chain 1; Myosin light chain 1 embryonic muscle/atrial isoform; Myosin light chain 4 alkali atrial embryonic; Myosin light chain alkali GT 1 isoform; Myosin light chain alkali GT-1 isoform; Myosin light polypeptide 4 alkali atrial embryonic; Myosin light polypeptide 4; myosin, atrial/fetal muscle, light chain; myosin light chain 1, embryonic muscle/atrial isoform
Cat.#:MYL4-5811HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human MYL4 Protein, GST-tagged
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Cat.#:MYL4-29362THTag:N/A
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human MYL4
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Cat.#:MYL4-30265THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MYL4, His-tagged
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Cat.#:MYL4-4751HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MYL4, His-tagged
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Cat.#:MYL4-6857HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Myosin, Light Chain 4, Alkali; Atrial, Embryonic, His-tagged
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Cat.#:Myl4-8029MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Myl4 protein, His-tagged
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Cat.#:MYL4-7028CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken MYL4
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Cat.#:MYL4-3085ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish MYL4
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Cat.#:MYL4-4026HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human MYL4 293 Cell Lysate
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Involved Pathway

MYL4 involved in several pathways and played different roles in them. We selected most pathways MYL4 participated on our site, such as Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, which may be useful for your reference. Also, other proteins which involved in the same pathway with MYL4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cardiac muscle contraction
COX7A2A; CACNG1; CACNB4A; COX6A1; CACNA1SA; UQCR11; CACNG2A; UQCRQ; SLC9A1; ACTC1A
Adrenergic signaling in cardiomyocytes
ATP1B1A; GNAS; CACNA2D3; CACNB3; CREB3L3L; VMHC; PLN; CAMK2G; MAPK14B; ATP1A3A

Protein Function

MYL4 has several biochemical functions, for example, actin filament binding, actin monomer binding, calcium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MYL4 itself. We selected most functions MYL4 had, and list some proteins which have the same functions with MYL4. You can find most of the proteins on our site.
Function
Related Protein
Function actin filament binding
Related Protein ERMN; CTNNA2; LASP1; CTNNAL1; TTN; ANTXR1; EZR; SMYHC2; SYNE3; TAGLN3B
Function actin monomer binding
Related Protein MYL2; MYL4; MKL1B; COBL; TWF2; COBLL1; TMSB15B; MTSS1; CORO1A; MKL1
Function calcium ion binding
Related Protein PKD1L3; MGP; PLSCR4; MYL5; EGFEM1; CDH20; BGLAP; PCDH2AB9; EFCAB10; PCDHB5
Function myosin II heavy chain binding
Related Protein MYL4; MYL3

Interacting Protein

MYL4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MYL4 here. Most of them are supplied by our site. Hope this information will be useful for your research of MYL4.
VCAM1; PYROXD2; FN1; ALB

MYL4 Related Articles

Lisowski, P; Juszczak, GR; et al. Stress susceptibility-specific phenotype associated with different hippocampal transcriptomic responses to chronic tricyclic antidepressant treatment in mice. BMC NEUROSCIENCE 14:-(2013).
Cheng, W; Yu, Z; et al. Perfluorooctane sulfonate (PFOS) induced embryotoxicity and disruption of cardiogenesis. TOXICOLOGY IN VITRO 27:1503-1512(2013).