Madcam1
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Official Full Name
mucosal vascular addressin cell adhesion molecule 1
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Overview
The protein encoded by this gene is an endothelial cell adhesion molecule that interacts preferentially with the leukocyte beta7 integrin LPAM-1 (alpha4beta7), L-selectin, and VLA-4 (alpha4beta1) on myeloid cells to direct leukocytes into mucosal and inf -
Synonyms
MADCAM1; mucosal vascular addressin cell adhesion molecule 1; mucosal addressin cell adhesion molecule 1; MACAM1; MAdCAM-1; hMAdCAM-1; mucosal addressin cell adhesion molecule-1;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- Rattus norvegicus (Rat)
- E.coli
- E.coli expression system
- HEK293
- HEK293T
- Mamanlian cells
- Mammalian Cell
- Mammalian cells
- Yeast
- C
- Fc
- Fc Chimera
- Avi
- Flag
- GST
- His
- His (Fc)
- His|Myc
- His|SUMO
- SUMO
- Myc
- DDK
- Myc|DDK
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
- Madcam1 Related Research Area
Madcam1 involved in several pathways and played different roles in them. We selected most pathways Madcam1 participated on our site, such as Cell adhesion molecules (CAMs), Intestinal i, ne network for IgA production, which may be useful for your reference. Also, other proteins which involved in the same pathway with Madcam1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|---|
Cell adhesion molecules (CAMs) | LRRC4B;ICOSLG;CD8B;MHC1UXA2;HLA-DPA1;BLA;CDH1;ICAM1;CNTN1A |
Intestinal i | HLA-DQA1;CD28;CD86;HLA-DRB4;HLA-DMA;IL6;MHC2DEB;CCR10;CCL25B |
ne network for IgA production | HLA-DMA;MADCAM1;MHC2A;ITGB7;HLA-DPB1;BLA;HLA-DRA;HLA-DOA;HLA-DQB1 |
Madcam1 has several biochemical functions, for example, integrin binding involved in cell-matrix adhesion. Some of the functions are cooperated with other proteins, some of the functions could acted by Madcam1 itself. We selected most functions Madcam1 had, and list some proteins which have the same functions with Madcam1. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
integrin binding involved in cell-matrix adhesion |
Madcam1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Madcam1 here. Most of them are supplied by our site. Hope this information will be useful for your research of Madcam1.
- Q&As
- Reviews
Q&As (5)
Ask a questionWhile its primary application is in IBD, researchers are exploring the potential of MADCAM1 in other inflammatory conditions.
Vedolizumab has shown efficacy in inducing and maintaining remission in patients with moderate to severe IBD.
Common side effects may include headache, abdominal pain, and respiratory tract infections, but it is generally considered a well-tolerated treatment.
Challenges include finding the right balance between immune suppression and maintaining immune function and addressing potential side effects.
MADCAM1 levels can be measured and used as a biomarker to assess disease activity and response to treatment in IBD patients.
Customer Reviews (3)
Write a reviewReputable manufacturers often provide technical support to researchers using MADCAM1 protein.
Manufacturers can ensure high-quality production of MADCAM1 protein, maintaining its purity and integrity.
This guarantees the reliability and reproducibility of research findings and eliminates potential issues arising from impurities or contamination.
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