Recombinant Mouse Mucosal Vascular Addressin Cell Adhesion Molecule 1

• Cat.No.: Madcam1-1767M

Specification

• Cat. No.: Madcam1-1767M
• Description: Mucosal vascular addressin cell adhesion molecule 1 (MAdCAM-1) is a multifunctional type l transmembrane adhesion molecule that is expressed selectively at venular sites of lymphocyte extravasation into mucosal lymphoid tissues and lamina propria, where it directs local lymphocyte trafficking. MAdCAM-1 is involved in the normal recirculation of lymphocytes between the blood and the gastrointestinal tract. MAdCAM-1 may be a relevant tissue-specific therapeutic target for the modulation of inflammatory bowel disease activity.
• Molecular Weight: The predicted molecular weight of Recombinant Mouse MAdCAM-1 is Mr 63 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 85-95 kDa.
• Source: Mammalian cells
• State Of Matter: Lyophilized.
• Purity: >95% by SDS Page and analyzed by silver stain.
• Endotoxin: <1.0 EU/µg as determined by the LAL method.
• Storage And Stability: This lyophilized protein is stable for six to twelve months when stored desiccated at -20°Cto -70°C. After aseptic reconstitution, this protein may be stored at 2°Cto 8°Cfor one month or at -20°Cto -70°Cin a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.

Gene Information

• Gene Name: Madcam1 mucosal vascular addressin cell adhesion molecule 1 [ Mus musculus ]
• Synonyms: Madcam1; mucosal vascular addressin cell adhesion molecule 1; AV211525; MGC35998; MGC144710; MGC144711
• Gene ID: 17123
• mRNA Refseq: NM_013591
• Protein Refseq: NP_038619
• UniProt ID: Q61826
• Chromosome Location: 10 C1-C2; 10 43.0 cM
• Pathway: Cell adhesion molecules (CAMs)
• Function: protein binding