pdcd4
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  • Official Full Name
  • programmed cell death 4 (neoplastic transformation inhibitor)
  • Background
  • This gene is a tumor suppressor and encodes a protein that binds to the eukaryotic translation initiation factor 4A1 and inhibits its function by preventing RNA binding. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010]
  • Synonyms
  • PDCD4; programmed cell death 4 (neoplastic transformation inhibitor); H731; programmed cell death protein 4; protein 197/15a; nuclear antigen H731; neoplastic transformation inhibitor protein;
Cat.#:PDCD4-1593HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PDCD4, GST-tagged
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Cat.#:PDCD4-175HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PDCD4
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Cat.#:PDCD4-30797THTag:
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human PDCD4
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Cat.#:PDCD4-484HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PDCD4 Protein, His-tagged
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Cat.#:PDCD4-12535MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse PDCD4 Protein
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Cat.#:PDCD4-3341RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey PDCD4 Protein, His-tagged
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Cat.#:PDCD4-5877CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken PDCD4
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Cat.#:PDCD4-1320HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human PDCD4 cell lysate
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Involved Pathway

PDCD4 involved in several pathways and played different roles in them. We selected most pathways PDCD4 participated on our site, such as Proteoglycans in cancer, MicroRNAs in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with PDCD4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Proteoglycans in cancer
ITGA2; PRKACB; WNT11; PRKCA; PDPK1; CAMK2B; WNT9B; GRB2; SLC9A1; RAC1
MicroRNAs in cancer
MAP2K1; RECK; CYP24A1; HDAC1; CDCA5; PIK3R2; VEGFA; TNC; APC; PRKCB

Protein Function

PDCD4 has several biochemical functions, for example, RNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PDCD4 itself. We selected most functions PDCD4 had, and list some proteins which have the same functions with PDCD4. You can find most of the proteins on our site.
Function
Related Protein
Function RNA binding
Related Protein RPL21; RAVER2; THOC2; RC3H2; RPL29; SARNP; ZMAT2; IGF2BP2A; HNRNPH1; NOL3
Function protein binding
Related Protein ECM1; MAGEA3; LSM6; MUTYH; NUDT21; FAM72A; PRMT5; PTPN6; NUP62; SLC22A5

Interacting Protein

PDCD4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PDCD4 here. Most of them are supplied by our site. Hope this information will be useful for your research of PDCD4.
EIF4A2; EIF4A1; RELA; EIF4A3; RPS13