Rabbit Anti-Human PDCD4 Polyclonal Antibody

• Cat.No.: CPBT-56410RH
• Product Overview: Rabbit Polyclonal antibody to Human PDCD4.

Specification

• Species: Human
• Source: Rabbit
• Tag: Non
• Antigen Description: This gene is a tumor suppressor and encodes a protein that binds to the eukaryotic translation initiation factor 4A1 and inhibits its function by preventing RNA binding. Alternative splicing results in multiple transcript variants.
• Isotype: IgG
• Immunogen: Synthetic peptide conjugated to KLH derived from within residues 450 to the C-terminus of Human PDCD4.
• Specificity: Up-regulated in proliferative cells. Highly expressed in epithelial cells of the mammary gland. Reduced expression in lung cancer and colon carcinoma.
• Formulation: Liquid
• Purity Detail: Immunogen affinity purified
• Applications: ICC/IF, WB
• Storage buffer: Preservative: 0.02% Sodium AzideConstituents: 1% BSA, PBS, pH 7.4
• Storage: Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Sequence similarities: Belongs to the PDCD4 family.Contains 2 MI domains.

Gene Information

• Gene Name: PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) [ Homo sapiens ]
• Official Symbol: PDCD4
• Synonyms: PDCD4; H731; MGC33046; MGC33047; programmed cell death 4 (neoplastic transformation inhibitor); programmed cell death protein 4; protein 197/15a; nuclear antigen H731; neoplastic transformation inhibitor protein; Nuclear antigen H731-like
• Gene ID: 27250
• mRNA Refseq: NM_014456
• Protein Refseq: NP_055271
• MIM: 608610
• UniProt ID: Q53EL6
• Chromosome Location: 10q24
• Pathway: mTOR signaling pathway
• Function: RNA binding; binding; protein binding