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Active Recombinant Full Length Human PDCD4 Protein

Cat.No. : PDCD4-365HF
Product Overview : Recombinant full length Human PDCD4 with proprietary tag; 77.7 kDa inclusive of tag. AAH31049
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Description : This gene is a tumor suppressor and encodes a protein that binds to the eukaryotic translation initiation factor 4A1 and inhibits its function by preventing RNA binding. Alternative splicing results in multiple transcript variants.
Source : In Vitro Cell Free System
Species : Human
Form : Liquid
Bio-activity : This product is useful for Antibody Production and Protein Array.
Molecular Mass : 77.700kDa inclusive of tags
Protein length : 470 amino acids
Purity : Proprietary Purification
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80 centigrade. Avoid freeze / thaw cycles.
Storage Buffer : pH: 8.00. Constituents:0.79% Tris HCl, 0.31% Glutathione.
Gene Name : PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) [ Homo sapiens ]
Official Symbol : PDCD4
Synonyms : PDCD4; programmed cell death 4 (neoplastic transformation inhibitor); programmed cell death protein 4; H731; nuclear antigen H731
Gene ID : 27250
mRNA Refseq : NM_001199492
Protein Refseq : NP_001186421
MIM : 608610
UniProt ID : Q53EL6

Not For Human Consumption!

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Customer Reviews (3)

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Reviews
04/03/2021

    Good solubility and stability in solution.

    01/27/2021

      The purity is good, and the results obtained after analysis by SDS-PAGE or Western blot are good.

      01/12/2021

        Short half-life and high clearance.

        Q&As (6)

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        Can PDCD4 be used as a target for sequencing signals? 02/21/2022

        Yes, PDCD4 is involved in the regulation of NF-κB signaling pathway and other biological processes of sequencing signals, and can be a target for sequencing signals.

        How can changes in the expression and function of PDCD4 be assessed? 11/14/2021

        Immunodeficiency method, Western blot, fluorescence microscopy and other techniques can be used to evaluate the changes in the expression and function of PDCD4.

        What is the role of PDCD4 in intestinal disease? 07/22/2021

        It may be involved in processes such as proliferation, apoptosis, and inflammatory response of intestinal epithelial cells, and is associated with intestinal diseases.

        What is the role of PDCD4 in neurological disorders? 12/25/2020

        PDCD4 may be related to neuronal apoptosis, neuroinflammatory response, etc. in neurological diseases.

        What is the relationship between PDCD4 and liver disease? 08/26/2020

        PDCD4 is involved in the regulation of hepatocyte growth, apoptosis and transformation, and may play a role in the occurrence and development of liver diseases.

        How can the information from PDCD4 be used for the development of therapeutic strategies? 08/13/2020

        Through in-depth study of the signaling pathways and regulatory mechanisms of PDCD4, we can provide important clues for the development of therapeutic strategies for related diseases.

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