pla2g10
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  • Official Full Name
  • phospholipase A2, group X
  • Background
  • Phospholipase A2 (PLA2) catalyzes the hydrolysis of the sn-2 position of membrane glycerophospholipids to liberate arachidonic acid (AA), a precursor of eicosanoids including prostaglandins and leukotrienes. The same reaction also produces lysophosholipi
  • Synonyms
  • PLA2G10; phospholipase A2, group X; group 10 secretory phospholipase A2; GXPLA2; Group X secretory phospholipase A2; GXSPLA2; Phosphatidylcholine 2 acylhydrolase GX; Phospholipase A2 group X; SPLA2; sPLA2X; sPLA2-X; GX sPLA2; OTTHUMP00000045725; phosphatidylcholine 2-acylhydrolase 10
Cat.#:PLA2G10-30733THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PLA2G10, His-tagged
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Cat.#:PLA2G10-70HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human phospholipase A2, group X, His-tagged
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Cat.#:PLA2G10-4484RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat PLA2G10 Protein
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Cat.#:PLA2G10-4098CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken PLA2G10
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Cat.#:PLA2G10-3145HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human PLA2G10 293 Cell Lysate
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Involved Pathway

PLA2G10 involved in several pathways and played different roles in them. We selected most pathways PLA2G10 participated on our site, such as Glycerophospholipid metabolism, Ether lipid metabolism, Arachidonic acid metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with PLA2G10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Glycerophospholipid metabolism
AGPAT9; PLA2G2F; GPD1C; CHPT1; GPD1L; PCYT1AB; LYPLA2; GPCPD1; PLA2G4D; PLA2G12A
Ether lipid metabolism
PAFAH1B1A; CEPT1; PAFAH1B1; GAL3ST1; PLA2G4B; PPAP2CB; PPAP2C; ENPP2; PPAP2D; PPAP2B
Arachidonic acid metabolism
PLA2G2F; CYP2C39; PLA2G2D; PTGS1; CYP2P6; CYP2P9; CYP4F18; CYP4A14; GPX7; ALOX12
Linoleic acid metabolism
PLA2G2A; CYP2J5; CYP2C19; PLB1; PLA2G2D; PLA2G2E; CYP2C54; CYP3A25; CYP2C50; CYP2C38
alpha-Linolenic acid metabolism
PLA2G6; PLA2G4A; PLA2G2A; PLA2G5; FADS2; PLA2G2D; PLA2G4F; PLA2G4AA; PLA2G4C; ACOX3
Metabolic pathways
LPCAT1; AMY1B; PRODH; CYP21A2; NANP; PCYT1BA; NAPRT; UQCR11; MAN1B1; SUCLG2
Ras signaling pathway
FOXO4; IKBKG; LAT; PIK3R3; RASA3; RASSF1; RASSF5; MAPK3; ANGPT4; MAPK8
Vascular smooth muscle contraction
MAPK1; PRKCHA; CALCRLA; ROCK2; PLA2G5; NPR2; RAF1A; ROCK2B; ARHGEF12; PRKCQ
Pancreatic secretion
CLCA5; SLC9A1; PLA2G2F; CELA3B; ATP1A1; ATP1A2; PLCB2; ATP1B3; PLA2G2A; CPA1
Fat digestion and absorption
PPAP2A; PLA2G10; DGAT2; SLC27A4; APOA1; GOT2; PLA2G2D; PLA2G1B; PNLIPRP2; MTTP

Protein Function

PLA2G10 has several biochemical functions, for example, calcium ion binding, phospholipase A2 activity, phospholipase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PLA2G10 itself. We selected most functions PLA2G10 had, and list some proteins which have the same functions with PLA2G10. You can find most of the proteins on our site.
Function
Related Protein
Function calcium ion binding
Related Protein PCDHGB3; DLK2; CBLB; MASP1; MYLPFB; CCDC48; ITIH1; LDLR; ELTD1; CRB2B
Function phospholipase A2 activity
Related Protein PLA2G4A; RARRES3; PLA2G2A; PLB1; PLA2G2E; PLA2G2F; OC90; LCAT; PLA2G10; PLA2G16
Function phospholipase activity
Related Protein Aadacl3; ABHD2B; CES1C; LIPG; ABHD6; Cel; NOTUM1A; LIPM; LIPC; PLA2G10

Interacting Protein

PLA2G10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PLA2G10 here. Most of them are supplied by our site. Hope this information will be useful for your research of PLA2G10.
MYO10

PLA2G10 Related Articles

Sin, BA; Akdis, M; et al. T-cell and antibody responses to phospholipase A(2) from different species show distinct cross-reactivity patterns. ALLERGY 66:1513-1521(2011).
Shaposhnik, Z; Wang, X; et al. The synergistic inhibition of atherogenesis in apoE(-/-) mice between pravastatin and the sPLA(2) inhibitor varespladib (A-002). JOURNAL OF LIPID RESEARCH 50:623-629(2009).