PLA2G10 Protein, phospholipase A2, group X


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Official Full Name phospholipase A2, group X
Background Phospholipase A2 (PLA2) catalyzes the hydrolysis of the sn-2 position of membrane glycerophospholipids to liberate arachidonic acid (AA), a precursor of eicosanoids including prostaglandins and leukotrienes. The same reaction also produces lysophosholipi
Synonyms PLA2G10; phospholipase A2, group X; group 10 secretory phospholipase A2; GXPLA2; Group X secretory phospholipase A2; GXSPLA2; Phosphatidylcholine 2 acylhydrolase GX; Phospholipase A2 group X; SPLA2; sPLA2X; sPLA2-X; GX sPLA2; OTTHUMP00000045725; phosphatidylcholine 2-acylhydrolase 10
    • Species :
    • Chicken
    • Human
    • Rat
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Tag :
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human PLA2G10-30733TH Recombinant Human PLA2G10, His-tagged E.coli His
    Human PLA2G10-3145HCL Recombinant Human PLA2G10 293 Cell Lysate HEK293 N/A
    Human PLA2G10-70H Recombinant Human phospholipase A2, group X, His-tagged E.coli His
    Rat PLA2G10-4484R Recombinant Rat PLA2G10 Protein Mammalian Cell His
    Chicken PLA2G10-4098C Recombinant Chicken PLA2G10 Mammalian Cell His

    PLA2G10 involved in several pathways and played different roles in them. We selected most pathways PLA2G10 participated on our site, such as Glycerophospholipid metabolism, Ether lipid metabolism, Arachidonic acid metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with PLA2G10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Glycerophospholipid metabolism LCLAT1; LCAT; PLA2G15; DGKB; PLD1; LYPLA2; LPCAT3; DGKD; GPD1B; LPIN2
    Ether lipid metabolism PPAP2B; ENPP6; ENPP2; CEPT1B; PLA2G4C; GAL3ST1A; CHPT1; PLA2G2F; LPCAT4; UGT8A
    Arachidonic acid metabolism CYP2C9; CYP2AD2; PTGDSB; CYP4F14; PTGS2A; PLA2G10; GPX1; CYP2C8; PTGDSA; DPEP1
    Linoleic acid metabolism CYP2C45; CYP2P8; PLA2G4A; PLA2G12A; PLA2G2A; CYP2C50; PLA2G4D; CYP2C70; CYP2C9; PLA2G6
    alpha-Linolenic acid metabolism PLA2G4C; PLA2G4A; PLA2G4F; PLA2G2A; PLA2G2F; PLA2G12B; ACAA1A; PLA2G12A; PLA2G2E; PLA2G3
    Metabolic pathways POLA1; PCYT1AA; GOT2B; LPIN3; NME3; ACADVL; UGT2B15; PLD1A; PPOX; KYNU
    Ras signaling pathway GNG5; INSR; GAB2; RASSF1; BAD; GNG7; FGF3; ARF6; PRKACG; ZAP70
    Vascular smooth muscle contraction PRKCHA; RHOAD; CALM1; ITPR1; GUCY1B3; RHOA; CALM1B; PLA2G4A; PPP1CB; RHOAB
    Pancreatic secretion PRSS1; CCKAR; PRSS2; PRSS3; PNLIPRP2; ATP1A1; SLC26A3; CPB1; TRPC1; ATP1B4
    Fat digestion and absorption PNLIPRP2; PPAP2B; MTTP; PLA2G2E; Cel; FABP2; PLA2G5; PPAP2C; MOGAT2; PLA2G12A

    PLA2G10 has several biochemical functions, for example, calcium ion binding, phospholipase A2 activity, phospholipase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PLA2G10 itself. We selected most functions PLA2G10 had, and list some proteins which have the same functions with PLA2G10. You can find most of the proteins on our site.

    Function Related Protein
    calcium ion binding MMP25; ANXA6; F9B; TLL1; EGFL8; CALRL2; FAT4; VCANB; NRXN1; F7
    phospholipase A2 activity PLA2G16; OC90; PLA2G4AA; PRDX6; PLA2G2F; PLA2G2D; ABHD3; PNPLA3; PLA2G2E; PLB1
    phospholipase activity PLA2G10; NOTUM1A; PLA2G4AA; ABHD2A; LIPH; Aadacl3; CES1C; LPL; PNPLA7; LIPN

    PLA2G10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PLA2G10 here. Most of them are supplied by our site. Hope this information will be useful for your research of PLA2G10.


    Sin, BA; Akdis, M; et al. T-cell and antibody responses to phospholipase A(2) from different species show distinct cross-reactivity patterns. ALLERGY 66:1513-1521(2011).
    Shaposhnik, Z; Wang, X; et al. The synergistic inhibition of atherogenesis in apoE(-/-) mice between pravastatin and the sPLA(2) inhibitor varespladib (A-002). JOURNAL OF LIPID RESEARCH 50:623-629(2009).

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