| Official Full Name | patatin-like phospholipase domain containing 3 |
| Background | The protein encoded by this gene is a triacylglycerol lipase that mediates triacylglycerol hydrolysis in adipocytes. The encoded protein, which appears to be membrane bound, may be involved in the balance of energy usage/storage in adipocytes. |
| Synonyms | PNPLA3; patatin-like phospholipase domain containing 3; adiponutrin , ADPN, C22orf20, chromosome 22 open reading frame 20; patatin-like phospholipase domain-containing protein 3; adiponutrin; dJ796I17.1; FLJ22012; Acylglycerol O acyltransferase; ADPN; C22orf20; Calcium independent phospholipase A2 epsilon; iPLA(2)epsilon; Patatin like phospholipase domain containing 3; iPLA2-epsilon; OTTHUMP00000197822; OTTHUMP00000197823; acylglycerol O-acyltransferase; calcium-independent phospholipase A2-epsilon |
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|
PNPLA3 involved in several pathways and played different roles in them. We selected most pathways PNPLA3 participated on our site, such as Glycerolipid metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with PNPLA3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Glycerolipid metabolism | ALDH3A2A; DGKE; MOGAT1; AKR1B8; AGPAT6; GPAM; LPIN1; LPIN2; AGPAT9; ALDH2.2 |
| Metabolic pathways | PPAP2C; ALDH6A1; GK2; AKR1B10; MIBP2; DLAT; GBA2; MVK; UGT1AB; ACSBG2 |
PNPLA3 has several biochemical functions, for example, diolein transacylation activity, mono-olein transacylation activity, phospholipase A2 activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PNPLA3 itself. We selected most functions PNPLA3 had, and list some proteins which have the same functions with PNPLA3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| diolein transacylation activity | PNPLA3 |
| mono-olein transacylation activity | PNPLA3 |
| phospholipase A2 activity | OC90; PNPLA3; PLA2G12B; PLA2G10; LCAT; PLA2G2E; PLA2G4D; PLA2G4A; RARRES3; PLA2G4AA |
| triglyceride lipase activity | LIPC; LPL; CES3; Cel; PNPLA2; CES1; CES5A; CEL.1; CES1D; PNPLA3 |
PNPLA3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PNPLA3 here. Most of them are supplied by our site. Hope this information will be useful for your research of PNPLA3.
AKT2; SNX27
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