pth
Share
  • Official Full Name
  • parathyroid hormone
  • Background
  • The protein encoded by this gene is a hormone secreted by parathyroid cells. This hormone elevates blood Ca2+ level by dissolving the salts in bone and preventing their renal excretion. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH).
  • Synonyms
  • hPTH; Parathormone; Parathyrin; Parathyroid hormone; Parathyroid hormone/parathyroid hormone-related peptide receptor; PTH; PTH/PTHr receptor; PTH/PTHrP type I receptor; PTH1 receptor; PTH1R; PTHR; PTHR1; PTHY-HUMAN; PTH C-terminal (a.a. 53-84)
Cat.#:PTH-01HTag:N/A
Source (Host):E.coliSpecies:Human
Product nameRecombinant Human PTH protein
+Inquiry
Cat.#:PTH-02HTag:N/A
Source (Host):E.coliSpecies:Human
Product nameRecombinant Human PTH protein
+Inquiry
Cat.#:PTH-03HTag:N/A
Source (Host):E.coliSpecies:Human
Product nameRecombinant Human PTH protein
+Inquiry
Cat.#:PTH-04HTag:N/A
Source (Host):E.coliSpecies:Human
Product nameRecombinant Human PTH protein
+Inquiry
Cat.#:PTH-152HTag:N/A
Source (Host):E.coliSpecies:Human
Product nameRecombinant Human PTH protein
+Inquiry
Cat.#:PTH-190HTag:Fc
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human Parathyroid Hormone, Fc Chimera
+Inquiry
Cat.#:PTH-2050HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PTH, His-tagged
+Inquiry
Cat.#:PTH-320HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human PTH
+Inquiry
Cat.#:PTH-503HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PTH Protein, GST-tagged
+Inquiry
Cat.#:PTH-640HTag:N/A
Source (Host):E.coliSpecies:Human
Product nameRecombinant Human PTH protein, N15-labeled
+Inquiry
Cat.#:PTH-83HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Parathyroid Hormone
+Inquiry
Cat.#:PTH-8562HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human PTH, Fc tagged
+Inquiry
Cat.#:Pth-7850MTag:His|GST
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Pth protein, His & GST-tagged
+Inquiry
Cat.#:PTH-4818RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat PTH Protein
+Inquiry
Cat.#:Pth-569RTag:His|MBP
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Pth protein, His & MBP-tagged
+Inquiry
Cat.#:PTH-7002CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken PTH
+Inquiry
Cat.#:PTH-7849CTag:His
Source (Host):E. coliSpecies:Chicken
Product nameRecombinant Chicken PTH protein, His-tagged
+Inquiry
Cat.#:PTH-2266BTag:His
Source (Host):E. coli or YeastSpecies:Bacillus subtilis
Product nameRecombinant Bacillus subtilis PTH protein, His-tagged
+Inquiry
Cat.#:PTH-7848CTag:His|GST
Source (Host):E. coliSpecies:Cattle
Product nameRecombinant Cattle PTH protein, His & GST-tagged
+Inquiry
Cat.#:PTH-7851PTag:His|GST
Source (Host):E. coliSpecies:Pig
Product nameRecombinant Pig PTH protein, His & GST-tagged
+Inquiry
Cat.#:PTH-1273HCLTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human PTH cell lysate
+Inquiry
Cat.#:Kit-1497Tag:N/A
Source (Host):Species:
Product namePTH Bioassay Kit
+Inquiry
Cat.#:PTH-191HTag:N/A
Source (Host):Species:Human
Product nameHuman Parathyroid Hormone Reference standard
+Inquiry
Cat.#:PTH-65HTag:N/A
Source (Host):Species:Human
Product nameParathyroid Hormone, Human-Type, Synthetic (1-34) fragment Reference standard
+Inquiry
Cat.#:PTH-66BTag:N/A
Source (Host):Species:Bovine
Product nameParathyroid Hormone, Bovine-Type, Synthetic (1-34) fragment Reference standard
+Inquiry
Cat.#:PTH-68BTag:N/A
Source (Host):Species:Bovine
Product nameBovine Parathyroid Hormone Reference standard
+Inquiry
Cat.#:PTH-P062HTag:N/A
Source (Host):N/ASpecies:Human
Product nameRecombinant Human PTH therapeutic protein
+Inquiry

Involved Pathway

PTH involved in several pathways and played different roles in them. We selected most pathways PTH participated on our site, such as Class B/2 (Secretin family receptors), Endochondral Ossification, G alpha (s) signalling events, which may be useful for your reference. Also, other proteins which involved in the same pathway with PTH were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Class B/2 (Secretin family receptors)
CALCB; FZD10; SCT; GNB3B; ADM2A; GCGA; EMR4; ADM; CRHR1; CALCRL
Endochondral Ossification
RUNX2A; CTSL2; CST5; COL2A1; SOX5; SERPINH1; ADAMTS5; NKX3.2; MGP; KIF3A
G alpha (s) signalling events
PTH; DRD5; PTH2; RLN3; RAMP1; CGA; CRHR2; SCT; ADCYAP1; ADORA2A
GPCR downstream signaling
NMUR1; CCR6; TAC3; LTB4R; OPN4; DRD5; TRIO; ADM2; ANXA1A; ADRA2C
GPCR ligand binding
CXCL13; UTS2; OPN4; ADRA2B; OXGR1; OPN1LW2; RAMP2; AGT; GPR65; EDNRAB
Osteoblast Signaling
SLC17A2; PTH
Signal Transduction
RBP4; KAL1A; ARAP1; GPR68; MYO9B; SOX6; DLC1; OXGR1A.2; ARHGAP40; EMR3
Signaling by GPCR
ARHGEF16; INSL5; PNOC; ARHGEF18; ARHGEF1B; GPR77; RGS17; OR52B4; UTS2; FGD4

Protein Function

PTH has several biochemical functions, for example, hormone activity, parathyroid hormone receptor binding, peptide hormone receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PTH itself. We selected most functions PTH had, and list some proteins which have the same functions with PTH. You can find most of the proteins on our site.
Function
Related Protein
Function hormone activity
Related Protein PYY; TG; EDN2; EDN1; GAST; PRL4A1; GCGA; POMCB; CGA; AMH
Function parathyroid hormone receptor binding
Related Protein PTH1B; PTH; PTH1A
Function peptide hormone receptor binding
Related Protein ADCYAP1; NPPA; LEP; NPPC; PTH; RUNDC3A; FYN; PTHLH; PTHLHA; JAK2
Function transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
Related Protein RELA; TFAP4; NKX2-5; FOXP3; MITF; NFIX; GATA6; SOX9; FOXF1; GATA5
Function type 1 parathyroid hormone receptor binding
Related Protein PTH

Interacting Protein

PTH has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PTH here. Most of them are supplied by our site. Hope this information will be useful for your research of PTH.
BAG6; FEZ1

PTH Related Articles

Pazianas, M; et al. Anabolic effects of PTH and the 'anabolic window'. TRENDS IN ENDOCRINOLOGY AND METABOLISM 26:111-113(2015).
Moe, SM; Chen, NX; et al. Anti-Sclerostin Antibody Treatment in a Rat Model of Progressive Renal Osteodystrophy. JOURNAL OF BONE AND MINERAL RESEARCH 30:539-549(2015).