PTH
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Official Full Name
parathyroid hormone
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Overview
The protein encoded by this gene is a hormone secreted by parathyroid cells. This hormone elevates blood Ca2+ level by dissolving the salts in bone and preventing their renal excretion. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH). -
Synonyms
hPTH; Parathormone; Parathyrin; Parathyroid hormone; Parathyroid hormone/parathyroid hormone-related peptide receptor; PTH; PTH/PTHr receptor; PTH/PTHrP type I receptor; PTH1 receptor; PTH1R; PTHR; PTHR1; PTHY-HUMAN; PTH C-terminal (a.a. 53-84);
- Recombinant Proteins
- Cell & Tissue Lysates
- Transfected Stable Cell Lines
- Therapeutic Proteins
- Protein Pre-coupled Magnetic Beads
- Assay Kits
- Bacillus subtilis
- Bovine
- Cattle
- Chicken
- Cynomolgus monkey
- Escherichia coli
- Human
- Mouse
- Pig
- Rat
- E. coli
- E. coli or Yeast
- E.coli
- HEK293
- HEK293 cells
- Human Cell
- Mammalian Cell
- Mammalian cells
- C
- His
- Fc
- GST
- His (Fc)
- Avi
- Myc
- His|GST
- His|MBP
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
- PTH Related Articles
PTH involved in several pathways and played different roles in them. We selected most pathways PTH participated on our site, such as Class B/2 (Secretin family receptors), Endochondral Ossification, G alpha (s) signalling events, which may be useful for your reference. Also, other proteins which involved in the same pathway with PTH were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Class B/2 (Secretin family receptors) | GHRH;ADCYAP1B;ADM2A;PTH;SCT;PTH2;EMR3;CALCRL;CALCB |
| Endochondral Ossification | SOX6;MMP13;CTSL2;KIF3A;ADAMTS1;ADAMTS4;RUNX3;COL10A1A;RUNX2A |
| G alpha (s) signalling events | GHRH;CALCA;RLN3A;NPS;GCGB;NPSR1;RXFP2;DRD5;ADRB3 |
| GPCR downstream signaling | CALCB;OPN4.1;RHOC;OR52B4;TRH;PROKR2;CRHB;NMUR1;NPB |
| GPCR ligand binding | NPFFR2;PPY;GPR31B;LTB4R;SSTR1;TAS2R16;GPR37B;ACKR4;GPBAR1 |
| Osteoblast Signaling | SLC17A2;PTH |
| Signal Transduction | SHB;EMR3;BCO2;INSL5;FSTL1;RDH7;DISP2;PRKCHB;RLN1 |
| Signaling by GPCR | NPB;TAS2R7;PENK;ACKR4;GAL;GPRC6A;OPN5;RGS21;TAAR1 |
PTH has several biochemical functions, for example, hormone activity, parathyroid hormone receptor binding, peptide hormone receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PTH itself. We selected most functions PTH had, and list some proteins which have the same functions with PTH. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| hormone activity | EPO;AVP;GCGA;LRSAM1;STC2A;IAPP;IGF3;GH2;CSHL1 |
| parathyroid hormone receptor binding | PTH1A;PTH1B;PTH |
| peptide hormone receptor binding | PTH;PTPN11;LEP;ADCYAP1;NPPA;NPPC;FYN;PTHLH;RUNDC3A |
| transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding | NR5A1;CEBPA;HIF1A;HNF1B;PKNOX1;SOX7;NKX2;PTH;FOXF1 |
| type 1 parathyroid hormone receptor binding |
PTH has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PTH here. Most of them are supplied by our site. Hope this information will be useful for your research of PTH.
BAG6; FEZ1
- Q&As
- Reviews
Customer Reviews (3)
Write a reviewThe PTH protein received was of stable composition and high concentration, giving me satisfactory experimental results.
The technical staff often communicate with me to understand the progress of my experiments and give timely responses to problems encountered in the experiments.
The company provides one-stop service, from product purchase to product delivery, it was very smooth.
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