sat1
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  • Official Full Name
  • spermidine/spermine N1-acetyltransferase 1
  • Background
  • The protein encoded by this gene belongs to the acetyltransferase family, and is a rate-limiting enzyme in the catabolic pathway of polyamine metabolism. It catalyzes the acetylation of spermidine and spermine, and is involved in the regulation of the intracellular concentration of polyamines and their transport out of cells. Defects in this gene are associated with keratosis follicularis spinulosa decalvans (KFSD). Alternatively spliced transcripts have been found for this gene.
  • Synonyms
  • SAT1; spermidine/spermine N1-acetyltransferase 1; diamine acetyltransferase 1; DC21; EC 2.3.1.57; KFSD; Polyamine N acetyltransferase 1; Polyamine N-acetyltransferase 1; Putrescine acetyltransferase; SAT; SAT1_HUMAN; Spermidine/spermine N(1) acetyltransferase 1; Spermidine/spermine N(1)-acetyltransferase 1; SSAT 1; SSAT; SSAT-1
Cat.#:SAT1-572HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SAT1 Protein, His-tagged
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Cat.#:Sat1-573RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Sat1 Protein, His-tagged
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Cat.#:SAT1-189HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SAT1, His-tagged
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Cat.#:SAT1-2515HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SAT1, GST-tagged
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Cat.#:SAT1-450HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human SAT1
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Cat.#:SAT1-4079RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey SAT1 Protein, His-tagged
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Cat.#:SAT1-5760CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken SAT1
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Cat.#:SAT1-2056HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human SAT1 293 Cell Lysate
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Cat.#:CBCRY21Tag:
Source (Host):E. coliSpecies:
Product nameDiamine Acetyltransferase 1
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Involved Pathway

SAT1 involved in several pathways and played different roles in them. We selected most pathways SAT1 participated on our site, such as Arginine and proline metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with SAT1 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Arginine and proline metabolism
ARG2; SAT1A.2; ALDH18A1; ALDH2.2; P4HA1A; AZIN2; SAT2B; CARNS1; DAO.2; GOT2
Metabolic pathways
DGKD; ACOX3; UGT1A6B; ctaG; UGT1A6A; NFS1; POLR2I; SDHD; GBGT1; udp

Protein Function

SAT1 has several biochemical functions, for example, diamine N-acetyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SAT1 itself. We selected most functions SAT1 had, and list some proteins which have the same functions with SAT1. You can find most of the proteins on our site.
Function
Related Protein
Function diamine N-acetyltransferase activity
Related Protein SAT1B; SAT2; SAT1A.1; SAT1; SAT1A.2

SAT1 Related Articles

Ehizibolo, DO; Perez, AM; et al. Epidemiological Analysis, Serological Prevalence and Genotypic Analysis of Foot-and-Mouth Disease in Nigeria 2008-2009. TRANSBOUNDARY AND EMERGING DISEASES 61:500-510(2014).
Tekleghiorghis, T; Moormann, RJM; et al. Serological Evidence Indicates that Foot-and-Mouth Disease Virus Serotype O, C and SAT1 are most Dominant in Eritrea. TRANSBOUNDARY AND EMERGING DISEASES 61:E83-E88(2014).