Recombinant Human SAT1 Protein, His-tagged

• Cat.No.: SAT1-572H
• Product Overview: Recombinant Human SAT1(Met1~Glu171) fused with His tag at N-terminal was expressed in E. coli.

Specification

• Description: The protein encoded by this gene belongs to the acetyltransferase family, and is a rate-limiting enzyme in the catabolic pathway of polyamine metabolism. It catalyzes the acetylation of spermidine and spermine, and is involved in the regulation of the intracellular concentration of polyamines and their transport out of cells. Defects in this gene are associated with keratosis follicularis spinulosa decalvans (KFSD). Alternatively spliced transcripts have been found for this gene.
• Source: E. coli
• Species: Human
• Tag: His
• Form: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Molecular Mass: 23.7kDa
• Protein length: Met1~Glu171
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
  If bio-activity of the protein is needed, please check active protein.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: SAT1 spermidine/spermine N1-acetyltransferase 1 [ Homo sapiens ]
• Official Symbol: SAT1
• Synonyms: SAT1; spermidine/spermine N1-acetyltransferase 1; SAT, spermidine/spermine N1 acetyltransferase; diamine acetyltransferase 1; diamine N acetyltransferase 1; SSAT; putrescine acetyltransferase; diamine N-acetyltransferase 1; polyamine N-acetyltransferase 1; spermidine/spermine N(1)-acetyltransferase 1; spermidine/spermine N1-acetyltransferase alpha; SAT; DC21; KFSD; KFSDX; SSAT-1
• Gene ID: 6303
• mRNA Refseq: NM_002970
• Protein Refseq: NP_002961
• MIM: 313020
• UniProt ID: P21673