Diamine Acetyltransferase 1

• Cat.No.: CBCRY21

Specification

• Source: E.coli
• Tag: Non
• Background: Spermidine/spermine N(1)-acetyltransferase (SSAT; EC 2.3.1.57) is a rate-limiting enzyme in the catabolic pathway of polyamine metabolism. It catalyzes the N(1)-acetylation of spermidine and spermine and, by the successive activity of polyamine oxidase, spermine can be converted to spermidine and spermidine to putrescine.
• Protein Classification: Transferase
• Structure Weight: 42238.60 Da
• Polymer: 1
• Molecule: Diamine acetyltransferase 1
• Chain Length: 179 amino acids
• PDB ID: 2G3T
• MMDB ID: 38382
• Method: X-Ray Diffraction
• Resolution: 1.8Å
• Reference: Zhu, Y.Q., Zhu, D.Y., Yin, L., Zhang, Y., Vonrhein, C., Wang, D.C. (2006) Crystal structure of human spermidine/spermine N1-acetyltransferase (hSSAT): the first structure of a new sequence family of transferase homologous superfamily Proteins 63: 1127-1131

Gene Information

• Gene Name: SAT1
• Synonyms: DC21; EC 2.3.1.57; KFSD; SAT; SSAT; SSAT-1;OTTHUMP00000023061; diamine N-acetyltransferase 1; diamine acetyltransferase 1; spermidine/spermine N1-acetyltransferase alpha; spermidine/spermine N1-acetyltransferase 1; Polyamine N-acetyltransferase 1; Putrescine acetyltransferase
• UniProt ID: P21673
• Gene ID: 6303
• Chromosome Location: Xp22.1
• Function: acyltransferase activity; diamine N-acetyltransferase activity; transferase activity