SERPINB8
-
Official Full Name
serpin peptidase inhibitor, clade B (ovalbumin), member 8
-
Overview
The superfamily of high molecular weight serine proteinase inhibitors (serpins) regulate a diverse set of intracellular;and extracellular processes such as complement activation, fibrinolysis, coagulation, cellular differentiation, tumor;suppression, apoptosis, and cell migration. Serpins are characterized by well-conserved a tertiary structure that;consists of 3 beta sheets and 8 or 9 alpha helices (Huber and Carrell, 1989 (PubMed 2690952)). A critical portion of;the molecule, the reactive center loop connects beta sheets A and C. Protease inhibitor-8 (PI8; SERPINB8) is a member;of the ov-serpin subfamily, which, relative to the archetypal serpin PI1 (MIM 107400), is characterized by a high;degree of homology to chicken ovalbumin, lack of N- and C-terminal extensions, absence of a signal peptide, and a;serine rather than an asparagine residue at the penultimate position (summary by Bartuski et al., 1997 (PubMed;9268635)). -
Synonyms
SERPINB8; serpin peptidase inhibitor, clade B (ovalbumin), member 8; PI8, serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 8; serpin B8; CAP2; cytoplasmic antiproteinase 2; CAP 2; CAP-2; OTTHUMP00000067000; OTTHUMP00000067001; Peptidase inhibitor 8; PI-8; PI8; Protease inhibitor 8 (ovalbumin type); Serine (or cysteine) proteinase inhibitor clade B (ovalbumin) member 8; Serpin peptidase inhibitor clade B (ovalbumin) member 8; SPB8_HUMAN; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 8;
- Recombinant Proteins
- Cell & Tissue Lysates
- Human
- Mouse
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Insect Cell
- Wheat Germ
- GST
- His
- Myc
- DDK
- Myc|DDK
- N/A
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
---|---|---|---|---|---|---|
Human | SERPINB8-686H | Recombinant Human serpin peptidase inhibitor, clade B (ovalbumin), member 8, His-tagged | E.coli | His | ||
Human | SERPINB8-31160TH | Recombinant Human SERPINB8 | Wheat Germ | N/A | 242 amino acids | |
Human | SERPINB8-2597H | Recombinant Human SERPINB8, GST-tagged | E.coli | GST | N-term-242aa | |
Human | SERPINB8-2250H | Recombinant Human SERPINB8 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Myc/DDK | ||
Human | SERPINB8-1005H | Recombinant Human SERPINB8 Protein, MYC/DDK-tagged | HEK293 | Myc/DDK | ||
Human | SERPINB8-465HF | Recombinant Full Length Human SERPINB8 Protein | In Vitro Cell Free System | 242 amino acids | ||
Mouse | SERPINB8-665MCL | Recombinant Mouse SERPINB8 cell lysate | Insect Cell | N/A |
- Involved Pathway
- Protein Function
- Interacting Protein
- SERPINB8 Related Articles
- SERPINB8 Related Research Area
SERPINB8 involved in several pathways and played different roles in them. We selected most pathways SERPINB8 participated on our site, such as Dissolution of Fibrin Clot, Hemostasis, which may be useful for your reference. Also, other proteins which involved in the same pathway with SERPINB8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|---|
Dissolution of Fibrin Clot | SERPINB8;SERPINE2;S100A10B;ANXA2;ANXA2B;HRG;S100A10A;ANXA2A;SERPINF2B |
Hemostasis | MAFGA;RHOB;CLEC1B;RAPGEF4;IRF1B;DGKB;NFE2;ATP2B3A;SPARC |
SERPINB8 has several biochemical functions, for example, protein binding, serine-type endopeptidase inhibitor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SERPINB8 itself. We selected most functions SERPINB8 had, and list some proteins which have the same functions with SERPINB8. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
protein binding | LDHD;MANBAL;ITGA2B;FKBP1B;ANXA2;AKR1A1;RAD18;TMEM66;TMEM140 |
serine-type endopeptidase inhibitor activity | SERPINF1;SERPINA1E;SPINK4;SERPINB1;SERPINB6;SERPINB1L4;SERPINF2B;CD109;PTI |
SERPINB8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SERPINB8 here. Most of them are supplied by our site. Hope this information will be useful for your research of SERPINB8.
- Q&As
- Reviews
Q&As (0)
Ask a questionAsk a Question for All SERPINB8 Products
Required fields are marked with *
My Review for All SERPINB8 Products
Required fields are marked with *