Recombinant Human SERPINB8 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: SERPINB8-2250H
• Product Overview: SERPINB8 MS Standard C13 and N15-labeled recombinant protein (NP_001027018) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The protein encoded by this gene is a member of the ov-serpin family of serine protease inhibitors. The encoded protein is produced by platelets and can bind to and inhibit the function of furin, a serine protease involved in platelet functions. In addition, this protein has been found to enhance the mechanical stability of cell-cell adhesion in the skin, and defects in this gene have been associated with an autosomal-recessive form of exfoliative ichthyosis.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 27.7 kDa
• AA Sequence: MDDLCEANGTFAISLFKILGEEDNS RNVFFSPMSISSALAMVFMGAKGST AAQMSQALCLYKDGDIHRGFQSLLS EVNRTGTQYLLRTANRLFGEKTCDF LPDFKEYCQKFYQAELEELSFAEDT EECRKHINDWVAEKTEGKISEVLDA GTVDPLTKLVLVNAIYFKGKWNEQF DRKYTRGMLFKTNEEKKTVQMMFKE AKFKMGYADEVHTQVLELPYVEEEL SMVILLPDDNTDLAVKETRTRPLEQ KLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: SERPINB8 serpin family B member 8 [ Homo sapiens (human) ]
• Official Symbol: SERPINB8
• Synonyms: SERPINB8; serpin peptidase inhibitor, clade B (ovalbumin), member 8; PI8, serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 8; serpin B8; CAP2; cytoplasmic antiproteinase 2; PI-8; peptidase inhibitor 8; protease inhibitor 8 (ovalbumin type); serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 8; PI8
• Gene ID: 5271
• mRNA Refseq: NM_001031848
• Protein Refseq: NP_001027018
• MIM: 601697
• UniProt ID: P50452