Sigirr
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Official Full Name
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
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Overview
Single Ig IL-1-related receptor is a protein that in humans is encoded by the SIGIRR gene. -
Synonyms
SIGIRR; single immunoglobulin and toll-interleukin 1 receptor (TIR) domain; single Ig IL-1-related receptor; single immunoglobulin domain IL1R1 related; TIR8; Single immunoglobulin domain containing IL1R related protein; Toll/interleukin 1 receptor 8; Ig IL1 related receptor; MGC110992; SIGIR_HUMAN; Single Ig IL 1 related receptor; Single Ig IL-1R-related molecule; Single Ig IL1R Related Molecule; Single immunoglobulin and toll interleukin 1 receptor (TIR) domain; Single immunoglobulin and toll interleukin 1 receptor domain; Single immunoglobulin domain-containing IL1R-related protein; TIR 8; Toll/interleukin-1 receptor 8; OTTHUMP00000229641; OTTHUMP00000229642; OTTHUMP00000229643; OTTHUMP00000229644; OTTHUMP00000229645; single immunoglobulin;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Rat
- Zebrafish
- E.coli
- HEK293
- HEK293T
- Human Cell
- Mammalian Cell
- Mammalian cells
- Yeast
- Fc
- hFc
- His
- His (Fc)
- Avi
- His|GST
- SUMO
- Myc
- DDK
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
- Sigirr Related Articles
- Sigirr Related Research Area
Sigirr involved in several pathways and played different roles in them. We selected most pathways Sigirr participated on our site, such as Activated TLR4 signalling, Immune System, Innate Immune System, which may be useful for your reference. Also, other proteins which involved in the same pathway with Sigirr were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Activated TLR4 signalling | DUSP3;S100B;PELI2;CHUK;TAB1;CHST13;DUSP4;TNIP2;PELI1 |
| Immune System | AGER;CD200R3;CFHL2;ASB7;OASL;UBE2F;DCTN6;ABI1;CISH |
| Innate Immune System | LGALS3;TXNIP;CFHL3;UNC93B1;LRRFIP1;NLRC5;DEFB125;NLRP4E;DUSP3 |
| MyD88:Mal cascade initiated on plasma membrane | SIGIRR;IRAK3 |
| Toll Like Receptor 2 (TLR2) Cascade | |
| Toll Like Receptor 4 (TLR4) Cascade | CD180;LY86;SIGIRR |
| Toll Like Receptor TLR1:TLR2 Cascade | |
| Toll Like Receptor TLR6:TLR2 Cascade |
Sigirr has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Sigirr itself. We selected most functions Sigirr had, and list some proteins which have the same functions with Sigirr. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | WDR6;TRIM31;RDH12;KRT25;PPP1R9B;CPNE3;TRA2B;ACPL2;RIPK1 |
Sigirr has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Sigirr here. Most of them are supplied by our site. Hope this information will be useful for your research of Sigirr.
RPN1; ENO2; yhdI
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