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SIGLEC7

  • Official Full Name

    sialic acid binding Ig-like lectin 7

  • Overview

    Sialic acid-binding Ig-like lectin 7 is a protein that in humans is encoded by the SIGLEC7 gene. SIGLEC7 has also been designated as CD328 (cluster of differentiation 328).
  • Synonyms

    SIGLEC7; sialic acid binding Ig-like lectin 7; sialic acid-binding Ig-like lectin 7; CD328; p75/AIRM1; QA79; SIGLEC 7; AIRM-1; QA79 membrane protein; sialic acid binding immunoglobulin-like lectin 7; adhesion inhibitory receptor molecule 1, siglec-7; p75;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Human
  • Rhesus monkey
  • E.coli
  • HEK293
  • Mammalian cells
  • C
  • Fc
  • hIgG1
  • hIgG4
  • His
  • His|S
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SIGLEC7-1797H Recombinant Human SIGLEC7 protein, His-tagged E.coli His Gly18~leu353
Human SIGLEC7-1798H Recombinant Human SIGLEC7 protein, His & S-tagged E.coli His/S Lys381~Lys467 (Accession # Q9Y286)
Human SIGLEC7-1846HCL Recombinant Human SIGLEC7 293 Cell Lysate HEK293 N/A
Human SIGLEC7-1845HCL Recombinant Human SIGLEC7 293 Cell Lysate HEK293 N/A
Human SIGLEC7-286H Active Recombinant Human SIGLEC7 protein, His-tagged HEK293 His Gln 19 - Leu 353
Human SIGLEC7-0688H Active Recombinant Human SIGLEC7 protein, Fc-tagged HEK293 Fc Gln19-Leu353
Human SIGLEC7-5805H Recombinant Human SIGLEC7 Protein (Met1-Leu353), C-Fc tagged Mammalian cells C-Fc Met1-Leu353
Human SIGLEC7-0689H Active Recombinant Human SIGLEC7 protein, Fc-tagged HEK293 Fc Gln19-Leu353
Human SIGLEC7-0690H Active Recombinant Human SIGLEC7 protein, His-Avi-tagged, Biotinylated HEK293 His-Avi Gln19-Leu353
Rhesus monkey SIGLEC7-1747R Recombinant Rhesus Monkey SIGLEC7 Protein, hIgG1-tagged HEK293 hIgG1
Rhesus monkey SIGLEC7-1748R Recombinant Rhesus Monkey SIGLEC7 Protein, hIgG4-tagged HEK293 hIgG4
Rhesus monkey SIGLEC7-1746R Recombinant Rhesus Monkey SIGLEC7 Protein HEK293 N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • SIGLEC7 Related Research Area

SIGLEC7 involved in several pathways and played different roles in them. We selected most pathways SIGLEC7 participated on our site, such as Adaptive Immune System, Immune System, Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell, which may be useful for your reference. Also, other proteins which involved in the same pathway with SIGLEC7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Adaptive Immune SystemKLRB1B;CXADR;AP2A2;ASB11;Siglece;DYNC1I1;CYBA;ACTR1B;CMTM2A
Immune SystemLGALS9;KPNA4;RAP1GAP2B;TRIM39;EIF4E3;TRIM3;SPSB1;DEFA6;ABI2
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cellICAM4;SIGLEC10;LILRA2;SIGLEC11;SIGLEC8;Mill2;SIGLEC7;CD200R3;CD200R1

SIGLEC7 has several biochemical functions, for example, carbohydrate binding, receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SIGLEC7 itself. We selected most functions SIGLEC7 had, and list some proteins which have the same functions with SIGLEC7. You can find most of the proteins on our site.

Function Related Protein
carbohydrate bindingPYGM;KLRD1;CD248;GCKR;CLEC10A;CLEC4A;SI;CLEC2G;LGALS2B
receptor activityLRP2;DERL1;LYVE1;TREM1;GRIN2A;TNFRSF9;PROCR;NEO1;CD46

SIGLEC7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SIGLEC7 here. Most of them are supplied by our site. Hope this information will be useful for your research of SIGLEC7.

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