Active Recombinant Human SIGLEC7 protein, Fc-tagged
Cat.No. : | SIGLEC7-0688H |
Product Overview : | Recombinant Human SIGLEC7 protein(Gln19-Leu353), fused with Fc tag, was expressed in HEK293. |
- Specification
- Gene Information
- Related Products
Source : | HEK293 |
Species : | Human |
Tag : | Fc |
Form : | Lyophilized from 0.22 μm filtered solution in 25 mM MES, 150 mM NaCl, pH5.5. Normally trehalose is added as protectant before lyophilization. |
Bio-activity : | Immobilized Human Siglec-7, Fc (L117A, L118A) Tag at 5 μg/mL (100 μL/well) can bind Neu5Aca2-6GalNAca-PAA-biotin with a linear range of 0.01-0.625 μg/mL. |
Molecular Mass : | This protein carries a Fc (L117A, L118A) tag at the C-terminus. The protein has a calculated MW of 63.3 kDa. The protein migrates as 70-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. Mutations (L117A, L118A/EU number: L234A/L235A) in human immunoglobulin G1 (hIgG1) Fc diminish binding to FcγRI leading to a significant reduction in ADCC and CDC in comparison to wild type human IgG1. |
Proteinlength : | Gln19-Leu353 |
Endotoxin : | Less than 0.01 EU per μg by the LAL method. |
Purity : | >95% as determined by SDS-PAGE. |
Storage : | Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | SIGLEC7 sialic acid binding Ig-like lectin 7 [ Homo sapiens ] |
Official Symbol : | SIGLEC7 |
Synonyms : | SIGLEC7; sialic acid binding Ig-like lectin 7; sialic acid-binding Ig-like lectin 7; CD328; p75/AIRM1; QA79; SIGLEC 7; AIRM-1; QA79 membrane protein; sialic acid binding immunoglobulin-like lectin 7; adhesion inhibitory receptor molecule 1, siglec-7; p75; AIRM1; CDw328; D-siglec; SIGLEC-7; |
Gene ID : | 27036 |
mRNA Refseq : | NM_014385 |
Protein Refseq : | NP_055200 |
MIM : | 604410 |
UniProt ID : | Q9Y286 |
Products Types
◆ Recombinant Protein | ||
SIGLEC7-0689H | Active Recombinant Human SIGLEC7 protein, Fc-tagged | +Inquiry |
SIGLEC7-1748R | Recombinant Rhesus Monkey SIGLEC7 Protein, hIgG4-tagged | +Inquiry |
SIGLEC7-1746R | Recombinant Rhesus Monkey SIGLEC7 Protein | +Inquiry |
SIGLEC7-1798H | Recombinant Human SIGLEC7 protein, His & S-tagged | +Inquiry |
SIGLEC7-5805H | Recombinant Human SIGLEC7 Protein (Met1-Leu353), C-Fc tagged | +Inquiry |
◆ Lysates | ||
SIGLEC7-1845HCL | Recombinant Human SIGLEC7 293 Cell Lysate | +Inquiry |
SIGLEC7-1846HCL | Recombinant Human SIGLEC7 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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