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Recombinant Rhesus Monkey SIGLEC7 Protein

Cat.No. : SIGLEC7-1746R
Product Overview : Recombinant Rhesus monkey SIGLEC7 Protein (XP_010367896 ( aa.18-352)) was expressed in human HEK293 cells.
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  • Gene Information
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Description : Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- and alpha-2,6-linked sialic acid. Also binds disialogangliosides (disialogalactosyl globoside, disialyl lactotetraosylceramide and disialyl GalNAc lactotetraoslylceramide). The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Mediates inhibition of natural killer cells cytotoxicity. May play a role in hemopoiesis. Inhibits differentiation of CD34+ cell precursors towards myelomonocytic cell lineage and proliferation of leukemic myeloid cells (in vitro).
Source : HEK293
Species : Rhesus monkey
Form : PBS, pH7.4.
Purity : > 95 %
Applications : ELISA; WB; Immunogen
Storage : -80 centigrade, Avoid freeze/thaw cycle.
Concentration : 1 mg/mL
Gene Name : SIGLEC7 sialic acid binding Ig like lectin 7 [ Rhinopithecus roxellana (golden snub-nosed monkey) ]
Official Symbol : SIGLEC7
Synonyms : SIGLEC7; sialic acid binding Ig-like lectin 7; sialic acid-binding Ig-like lectin 7; CD328; p75/AIRM1; QA79; SIGLEC 7; AIRM-1; QA79 membrane protein; sialic acid binding immunoglobulin-like lectin 7; adhesion inhibitory receptor molecule 1; siglec-7; p75; AIRM1; CDw328; D-siglec; SIGLEC-7;
Gene ID : 104667258
mRNA Refseq : XM_010369594.1
Protein Refseq : XP_010367896

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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