SIRT2 involved in several pathways and played different roles in them. We selected most pathways SIRT2 participated on our site, such as Signaling events mediated by HDAC Class I, Signaling events mediated by HDAC Class III, which may be useful for your reference. Also, other proteins which involved in the same pathway with SIRT2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

SIRT2 has several biochemical functions, for example, NOT NAD+ ADP-ribosyltransferase activity, NAD+ binding, NAD-dependent histone deacetylase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SIRT2 itself. We selected most functions SIRT2 had, and list some proteins which have the same functions with SIRT2. You can find most of the proteins on our site.

SIRT2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SIRT2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SIRT2.

BUB1B; KAT2B; RELA; CDC14B; G6PD; RIPK3; MYOD1; HDAC6