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Recombinant Rat SIRT2 Protein

Cat.No. : SIRT2-5408R
Product Overview : Recombinant Rat SIRT2 full length or partial length protein was expressed.
  • Specification
  • Gene Information
  • Related Products
Source : Mammalian Cells
Species : Rat
Tag : His
Form : Liquid or lyophilized powder
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method.
Purity : >80%
Notes : This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
Storage : Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC.
Storage Buffer : PBS buffer
Gene Name : Sirt2 sirtuin 2 [ Rattus norvegicus ]
Official Symbol : SIRT2
Gene ID : 361532
mRNA Refseq : NM_001008368.1
Protein Refseq : NP_001008369.1
MIM :
UniProt ID : Q5RJQ4

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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How does SIRT2 participate in the regulation of cellular stress responses? 02/09/2022

SIRT2 is involved in stress response pathways, deacetylating and modulating the activity of stress-responsive proteins, contributing to cellular adaptation to various stress conditions.

How does SIRT2 contribute to the regulation of cellular metabolism? 07/15/2021

SIRT2 influences cellular metabolism by deacetylating enzymes involved in glycolysis, fatty acid metabolism, and mitochondrial function, impacting overall energy homeostasis.

Explain the molecular mechanisms underlying SIRT2-mediated deacetylation of target proteins. 11/30/2020

SIRT2 uses NAD+ as a cofactor to remove acetyl groups from lysine residues, a process that links cellular metabolic state to protein acetylation and deacetylation.

Discuss the role of SIRT2 in the regulation of cell cycle progression. 08/19/2019

SIRT2 influences cell cycle progression by deacetylating key regulators, such as cyclin-dependent kinases (CDKs) and checkpoint proteins, impacting cell cycle checkpoints and progression.

Discuss the role of SIRT2 in neurodegenerative diseases and its potential as a therapeutic target. 01/04/2018

SIRT2 has been implicated in neurodegenerative diseases, and modulating its activity is explored as a potential therapeutic strategy for conditions such as Parkinson's disease.

Customer Reviews (3)

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Reviews
04/15/2021

    Efficient and knowledgeable customer service—made our purchase straightforward.

    11/02/2020

      This recombined protein is our go-to for dependable and accurate results.

      08/30/2018

        Punctual delivery is crucial, and this product arrived right on time.

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