snai1
Share
  • Official Full Name
  • snail homolog 1
  • Background
  • Snail is a zinc-finger transcription factor that can repress E-cadherin transcription. Downregulation of E-cadherin is associated with epithelial-mesenchymal transition during embryonic development, a process also exploited by invasive cancer cells (1-3).
  • Synonyms
  • SNAI1; snail homolog 1 (Drosophila); snail 1 (drosophila homolog), zinc finger protein; zinc finger protein SNAI1; SLUGH2; SNA; SNAH; SNAIL; SNAIL1; protein sna; snail 1 homolog; protein snail homolog 1; snail 1 zinc finger protein; snail 1, zinc finger p
Cat.#:SNAI1-16HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human SNAI1, MYC/DDK-tagged
+Inquiry
Cat.#:SNAI1-178HTag:T7/His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SNAI1 protein, T7/His-tagged
+Inquiry
Cat.#:SNAI1-30016THTag:
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human SNAI1
+Inquiry
Cat.#:SNAI1-330HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human snail family zinc finger 1, His-tagged
+Inquiry
Cat.#:SNAI1-15660MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse SNAI1 Protein
+Inquiry
Cat.#:SNAI1-6699CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken SNAI1
+Inquiry
Cat.#:SNAI1-1643HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human SNAI1 293 Cell Lysate
+Inquiry

Involved Pathway

SNAI1 involved in several pathways and played different roles in them. We selected most pathways SNAI1 participated on our site, such as Adherens junction, which may be useful for your reference. Also, other proteins which involved in the same pathway with SNAI1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Adherens junction
RAC3A; ACTB; PTBP3; MAPK1; TCF7L2; YES1; WASLB; INSR; SMAD2; PTPN6

Protein Function

SNAI1 has several biochemical functions, for example, RNA polymerase II regulatory region sequence-specific DNA binding, kinase binding, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SNAI1 itself. We selected most functions SNAI1 had, and list some proteins which have the same functions with SNAI1. You can find most of the proteins on our site.
Function
Related Protein
Function RNA polymerase II regulatory region sequence-specific DNA binding
Related Protein AEBP1; ZNF792; HOXD8; ZFP39; NFIL3; PRDM12B; PCGF6; TRPS1; SP1; NME2
Function kinase binding
Related Protein WWC2; SNAI1; SLC2A1; STRADA; DLG4; HPCA; SRC; PRPSAP1; JAKMIP2; DGKQ
Function metal ion binding
Related Protein CARS; ZFP524; CYP2J5; CYP2AA9; PPM1K; ZNF488; ZFP553; CYP2B19; RPE65A; EXTL3
Function protein binding
Related Protein TRIAP1; SYTL2; R3HDM2; ANKRD10; TCTN2; FBP1; DTL; KRT20; METTL17; DPF2
Function transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
Related Protein NKX3-2; NFIL3; PRDM1; PROX1; NFATC4; NFIL3-4; CUX2; SALL1; ESRRA; NFIL3-2

Interacting Protein

SNAI1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SNAI1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SNAI1.
KDM1A

SNAI1 Related Articles

Li, ZD; Wermuth, PJ; et al. Caveolin-1 Deficiency Induces Spontaneous Endothelial-to-Mesenchymal Transition in Murine Pulmonary Endothelial Cells in Vitro. AMERICAN JOURNAL OF PATHOLOGY 182:325-331(2013).
Ohnuki, K; Umezono, T; et al. Expression of transcription factor Snai1 and tubulointerstitial fibrosis in progressive nephropathy. JOURNAL OF NEPHROLOGY 25:233-239(2012).