sub1
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  • Official Full Name
  • SUB1 SUB1 homolog (S. cerevisiae)
  • Background
  • The human PC4 (also called p15) is a non-TAF transcription coactivator that mediates activator-dependent transcription by RNA polymerase II in vitro through most tested activators. The function of PC4 is apparently through interactions with transcriptional activators and the basal transcription machinery. It is negatively regulated by casein kinase II phosphorylation both in vivo and in vitro. PC4 strongly binds single stranded DNA and regulates HSSB (RPA)-dependent SV40 DNA replication. Recent studies indicated that PC4 can be acetylated by several histone acetyltransferase.
  • Synonyms
  • SUB1; SUB1 homolog (S. cerevisiae); activated RNA polymerase II transcriptional coactivator p15; p14; p15; PC4; positive cofactor 4; activated RNA polymerase II transcription cofactor 4; P15; MGC102747;
Cat.#:SUB1-1080HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SUB1 Homolog(S. cerevisiae)
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Cat.#:SUB1-2499HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SUB1 Homolog(S. cerevisiae), His-tagged
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Cat.#:SUB1-3040HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SUB1, GST-tagged
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Cat.#:SUB1-30794THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SUB1, His-tagged
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Cat.#:SUB1-31457THTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SUB1
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Cat.#:SUB1-562HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SUB1, His tagged
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Cat.#:SUB1-16206MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse SUB1 Protein
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Cat.#:Sub1-3110MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse Sub1, His-tagged
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Cat.#:SUB1-5822RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat SUB1 Protein
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Cat.#:SUB1-987CTag:His
Source (Host):Mammalian CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus SUB1 Protein, His-tagged
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Cat.#:SUB1-4554RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey SUB1 Protein, His-tagged
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Cat.#:SUB1-1857CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken SUB1
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Cat.#:SUB1-1368HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human SUB1 293 Cell Lysate
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Protein Function

SUB1 has several biochemical functions, for example, poly(A) RNA binding, protein binding, single-stranded DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SUB1 itself. We selected most functions SUB1 had, and list some proteins which have the same functions with SUB1. You can find most of the proteins on our site.
Function
Related Protein
Function poly(A) RNA binding
Related Protein MADD; PCBP3; PABPC4; NSUN2; RPS28; LARP7; RPL29; CCT6A; FASTKD2; WDR46
Function protein binding
Related Protein BDKRB2; NUMBL; PSMB5; TPR; MUM1; SHE; DSP; XPO5; CLK4; IARS
Function single-stranded DNA binding
Related Protein CSDA; RAD51; LUZP4; NABP1A; MLH3; ERCC4; RAD51L3; NCL; XRCC3; IGHMBP2
Function transcription coactivator activity
Related Protein GATA3; TAF11; RFXAP; TFDP1A; PRDM16; ABT1; NCOA3; MED16; CDK7; MLL5
Function transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding
Related Protein HMGA1; CUX1; SFPI1; HCFC1; CDX1; PROP1; SUB1; TARDBP; FOXH1; MIXL1

Interacting Protein

SUB1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SUB1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SUB1.
CSNK2A1; tat_hv112; Rep68; CSTF2; Rep40; Kif1c; Shoc2; CSTF2; Rep78; PINX1; midostaurin