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SerpinB1

  • Official Full Name

    serpin peptidase inhibitor, clade B (ovalbumin), member 1

  • Overview

    Leukocyte elastase inhibitor (LEI) also known as serpin B1 is a protein that in humans is encoded by the SERPINB1 gene.
  • Synonyms

    SERPINB1; serpin peptidase inhibitor, clade B (ovalbumin), member 1; ELANH2, serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 1; leukocyte elastase inhibitor; anti elastase; EI; PI2; ELANH2; ILEU_HUMAN; LEI; M/NEI; MNEI; Monocyte/neutrophil elastase inhibitor; Peptidase inhibitor 2; Pi-2; Serine (or cysteine) proteinase inhibitor clade B (ovalbumin) member 1; Serpin B1; Serpin peptidase inhibitor clade B (ovalbumin) member 1; anti-elastase; protease inhibitor 2 (anti-elastase), monocyte/neutrophil derived; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Pig
  • Rhesus Macaque
  • Zebrafish
  • Baculovirus-Insect cells
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Insect Cell
  • Insect Cells
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • C
  • His
  • Flag
  • His (Fc)
  • Avi
  • Myc
  • SUMO
  • Myc|DDK
  • N/A
  • N
  • Tag Free
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SerpinB1-3981H Recombinant Human SerpinB1 protein, His-tagged Insect Cells His Met1-Pro379
Human SERPINB1-31161TH Recombinant Human SERPINB1 Wheat Germ N/A 100 amino acids
Human SERPINB1-90H Recombinant Human SERPINB1 protein, His-tagged E.coli His 394aa(including fusion tag)
Human SERPINB1-31187TH Recombinant Human SERPINB1 Wheat Germ N/A 379 amino acids
Human SERPINB1-778H Recombinant Human SERPINB1 Protein, His-tagged E.coli His
Human SERPINB1-578HCL Recombinant Human SERPINB1 cell lysate Insect Cell N/A
Human SERPINB1-5735H Recombinant Human SERPINB1 Protein (Met1-Pro379), C-His tagged Mammalian cells C-His Met1-Pro379
Human SERPINB1-857H Recombinant Human SERPINB1 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human SERPINB1-3480H Recombinant Human SERPINB1 protein, His-SUMO-tagged E.coli His-SUMO 1-379aa
Human SERPINB1-463HF Recombinant Full Length Human SERPINB1 Protein In Vitro Cell Free System 379 amino acids
Human SERPINB1-1975H-B Recombinant Human SERPINB1 Protein Pre-coupled Magnetic Beads HEK293
Human SERPINB1-1975H Recombinant Human SERPINB1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human SERPINB1-5737H Recombinant Human SERPINB1 Protein (Leu13-Leu252), N-His tagged E.coli N-His Leu13-Leu252
Human SERPINB1-219HFL Active Recombinant Full Length Human SERPINB1 Protein, C-Flag-tagged Mammalian cells Flag
Human SERPINB1-0055H Recombinant Human SERPINB1 Protein (Full Length), Tag Free Baculovirus-Insect cells Tag Free Full Length
Rhesus Macaque SERPINB1-4149R Recombinant Rhesus monkey SERPINB1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque SERPINB1-3966R Recombinant Rhesus Macaque SERPINB1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque SERPINB1-3966R-B Recombinant Rhesus Macaque SERPINB1 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish SERPINB1-763Z Recombinant Zebrafish SERPINB1 Mammalian Cell His
Pig SERPINB1-3481P Recombinant Pig SERPINB1 protein, His&Myc-tagged E.coli His&Myc 1-378aa
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • SerpinB1 Related Articles
  • SerpinB1 Related Research Area

SerpinB1 involved in several pathways and played different roles in them. We selected most pathways SerpinB1 participated on our site, such as Amoebiasis, which may be useful for your reference. Also, other proteins which involved in the same pathway with SerpinB1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
AmoebiasisTLR4;SERPINB6;SERPINB1A;NOS2;PIK3R5;TNF;SERPINB6B;PLCB3;LAMA2

SerpinB1 has several biochemical functions, for example, serine-type endopeptidase inhibitor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SerpinB1 itself. We selected most functions SerpinB1 had, and list some proteins which have the same functions with SerpinB1. You can find most of the proteins on our site.

Function Related Protein
serine-type endopeptidase inhibitor activityCOL6A3;SERPINB2;SERPINH2;SERPINB5;HRG;PTI;SERPINF2B;SERPINB6;COL7A1

SerpinB1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SerpinB1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SerpinB1.

icmF2; q9k5j5_bacan; 1-phosphatidyl-1d-myo-inositol 4,5-bisphosphate

Jiang, HW; Jin, CM; et al. Next Generation Sequencing Analysis of miRNAs: MiR-127-3p Inhibits Glioblastoma Proliferation and Activates TGF-beta Signaling by Targeting SKI. OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY 18:196-206(2014).
  • Q&As
  • Reviews

Q&As (7)

Ask a question
How does SERPINB1 contribute to the regulation of protease activity? 02/26/2021

It inhibits neutrophil elastase and cathepsin G, balancing proteolysis.

What are the molecular mechanisms regulating SERPINB1 expression and activity? 08/05/2020

Its expression and activity are regulated by various signaling pathways and transcription factors.

Are there therapeutic applications targeting SERPINB1? 07/01/2020

Potential therapeutic applications could involve modulating SERPINB1 to mitigate damage in inflammatory and infectious diseases.

What role does SERPINB1 play in inflammatory responses? 12/21/2019

It helps control inflammation by modulating protease activity in immune responses.

What is the main function of SERPINB1 in cellular processes? 12/17/2018

SERPINB1 functions as a serine protease inhibitor, regulating protease activity.

How is SERPINB1 implicated in diseases related to inflammation and infection? 07/27/2018

SERPINB1 protects tissues from damage during inflammation and infection.

In which cells or tissues is SERPINB1 predominantly expressed? 05/13/2018

SERPINB1 is predominantly expressed in neutrophils and some other immune cells.

Customer Reviews (3)

Write a review
Reviews
06/14/2022

    Quick, efficient, reliable service.

    12/28/2021

      Worked great, highly pure.

      05/12/2021

        Excellent for molecular experiments.

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