Recombinant Human SERPINB1 Protein, His-tagged
Cat.No. : | SERPINB1-778H |
Product Overview : | Recombinant Human SERPINB1 fused with His tag at N-terminal was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a member of the serpin family of proteinase inhibitors. Members of this family maintain homeostasis by neutralizing overexpressed proteinase activity through their function as suicide substrates. This protein inhibits the neutrophil-derived proteinases neutrophil elastase, cathepsin G, and proteinase-3 and thus protects tissues from damage at inflammatory sites. Alternative splicing results in multiple transcript variants. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 100 mM Arg. Store at -80 centigrade. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions. |
Molecular Mass : | 42.7 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 [ Homo sapiens ] |
Official Symbol : | SERPINB1 |
Synonyms : | SERPINB1; serpin peptidase inhibitor, clade B (ovalbumin), member 1; ELANH2, serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 1; leukocyte elastase inhibitor; anti elastase; EI; PI2; PI-2; serpin B1; anti-elastase; peptidase inhibitor 2; monocyte/neutrophil elastase inhibitor; protease inhibitor 2 (anti-elastase), monocyte/neutrophil derived; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 1; LEI; MNEI; M/NEI; ELANH2; |
Gene ID : | 1992 |
mRNA Refseq : | NM_030666 |
Protein Refseq : | NP_109591 |
MIM : | 130135 |
UniProt ID : | P30740 |
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◆ Lysates | ||
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionIt inhibits neutrophil elastase and cathepsin G, balancing proteolysis.
Its expression and activity are regulated by various signaling pathways and transcription factors.
Potential therapeutic applications could involve modulating SERPINB1 to mitigate damage in inflammatory and infectious diseases.
It helps control inflammation by modulating protease activity in immune responses.
SERPINB1 functions as a serine protease inhibitor, regulating protease activity.
SERPINB1 protects tissues from damage during inflammation and infection.
SERPINB1 is predominantly expressed in neutrophils and some other immune cells.
Customer Reviews (3)
Write a reviewQuick, efficient, reliable service.
Worked great, highly pure.
Excellent for molecular experiments.
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