trpv1
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  • Official Full Name
  • transient receptor potential cation channel, subfamily V, member 1
  • Background
  • The transient receptor potential cation channel subfamily V member 1 (TrpV1), also known as the capsaicin receptor and the vanilloid receptor 1, is a protein that, in humans, is encoded by the TRPV1 gene. It was the first isolated member of the transient receptor potential vanilloid receptor proteins which in turn are a sub family of the transient receptor potential protein group. This protein is a member of the TRPV group of transient receptor potential family of ion channels.
  • Synonyms
  • Trpv1; transient receptor potential cation channel, subfamily V, member 1; Vr1; Vr1l1; VR.5"sv; transient receptor potential cation channel subfamily V member 1; OTRPC1; capsaicin receptor; vanilloid receptor 1;; osm-9-like TRP channel 1; vanilloid type 1 receptor; vanilloid receptor subtype 1; vanilloid receptor type 1 like protein 1
Cat.#:TRPV1-345HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human TRPV1 Protein, His-tagged
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Cat.#:TRPV1-17461MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse TRPV1 Protein
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Cat.#:TRPV1-6303RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat TRPV1 Protein
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Cat.#:TRPV1-6141CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken TRPV1
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Cat.#:TRPV1-6716ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish TRPV1
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Cat.#:TRPV1-734HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human TRPV1 293 Cell Lysate
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Cat.#:TRPV1-735HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human TRPV1 293 Cell Lysate
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Involved Pathway

TRPV1 involved in several pathways and played different roles in them. We selected most pathways TRPV1 participated on our site, such as Neuroactive ligand-receptor interaction, Inflammatory mediator regulation of TRP channels, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRPV1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Neuroactive ligand-receptor interaction
OPRL1; GRM4; CHRNB3B; FSHR; F2RL1; ADORA3; OPRM1; CHRNB3A; DRD7; GABBR1
Inflammatory mediator regulation of TRP channels
NTRK1; F2RL1; HRH1; ASIC4; PIK3R1; PLCB4; ASIC2; PLA2G4F; PRKCG; CYP4A12A

Protein Function

TRPV1 has several biochemical functions, for example, ATP binding, calcium channel activity, calcium-release channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TRPV1 itself. We selected most functions TRPV1 had, and list some proteins which have the same functions with TRPV1. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein ERBB4; MAPK12A; MOV10; INSR; HELB; LRGUK; ABCA13; MTHFD1; LCK; FAM20B
Function calcium channel activity
Related Protein RYR1B; CACNG2B; TRPV3; TRPC5; SLC24A1; P2RX1; SLC24A4; TRPV6; TRPC2; TRPC6A
Function calcium-release channel activity
Related Protein RYR1; RYR3; JPH2; RYR2; TRPV1; JPH3; RASA3
Function calmodulin binding
Related Protein PNCK; CAMK1GB; PDE1C; TRPV5; CNN2; CNN1A; TRPV4; MKNK2; CNN1; PCP4
Function excitatory extracellular ligand-gated ion channel activity
Related Protein TRPV1
Function phosphoprotein binding
Related Protein MID2; DPYS; SAG; ARR3; SNCA; SERPINB1A; DPYSL3; PIH1D1; GPRIN1; CSNK1D
Function transmembrane signaling receptor activity
Related Protein TRPV1; CD4; OR4N4; LGR5; FZD7B; GABRQ; Fzd4; ANTXR1; ICAM1; AGER

TRPV1 Related Articles

Solorzano, C; Villafuerte, D; et al. Primary Afferent and Spinal Cord Expression of Gastrin-Releasing Peptide: Message, Protein, and Antibody Concerns. JOURNAL OF NEUROSCIENCE 35:648-657(2015).
Moriya, T; Shibasaki, R; et al. Full-length transient receptor potential vanilloid 1 channels mediate calcium signals and possibly contribute to osmoreception in vasopressin neurones in the rat supraoptic nucleus. CELL CALCIUM 57:25-37(2015).
Ruan, Z; Wang, HM; et al. A novel caffeoyl triterpene attenuates cerebral ischemic injury with potent anti-inflammatory and hypothermic effects. JOURNAL OF NEUROCHEMISTRY 133:93-103(2015).