wif1
Share
  • Official Full Name
  • WNT inhibitory factor 1
  • Background
  • The protein encoded by this gene functions to inhibit WNT proteins, which are extracellular signaling molecules that play a role in embryonic development. This protein contains a WNT inhibitory factor (WIF) domain and five epidermal growth factor (EGF)-like domains, and is thought to be involved in mesoderm segmentation. This gene functions as a tumor suppressor gene, and has been found to be epigenetically silenced in various cancers. [provided by RefSeq, Jun 2010]
  • Synonyms
  • WIF1; WNT inhibitory factor 1; WIF-1
Cat.#:WIF1-359HTag:Myc|DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human WIF1 Protein, MYC/DDK-tagged
+Inquiry
Cat.#:WIF1-163HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human WIF1 Protein, His-tagged
+Inquiry
Cat.#:WIF1-268HTag:His
Source (Host):NS0Species:Human
Product nameRecombinant Human WIF1 protein, His-tagged
+Inquiry
Cat.#:WIF1-30862THTag:His
Source (Host):Insect cellsSpecies:Human
Product nameRecombinant Human WIF1 protein, His-tagged
+Inquiry
Cat.#:WIF1-3730HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human WIF1, His-tagged
+Inquiry
Cat.#:WIF1-516HTag:His
Source (Host):High-5 insect cellsSpecies:Human
Product nameRecombinant Human WNT Inhibitory Factor 1, His-tagged
+Inquiry
Cat.#:WIF1-577HTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human WIF1 protein
+Inquiry
Cat.#:Wif1-372MTag:His
Source (Host):Insect cellSpecies:Mouse
Product nameRecombinant Mouse Wif1 Protein, His-tagged
+Inquiry
Cat.#:Wif1-7410MTag:His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Wif1, His tagged
+Inquiry
Cat.#:Wif1-1895RTag:His|T7
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Wif1 protein, His & T7-tagged
+Inquiry
Cat.#:WIF1-6590RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat WIF1 Protein
+Inquiry
Cat.#:WIF1-5216RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey WIF1 Protein, His-tagged
+Inquiry
Cat.#:WIF1-4419CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken WIF1
+Inquiry
Cat.#:WIF1-8828ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish WIF1
+Inquiry
Cat.#:WIF1-1525MCLTag:N/A
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse WIF1 cell lysate
+Inquiry

Involved Pathway

WIF1 involved in several pathways and played different roles in them. We selected most pathways WIF1 participated on our site, such as Negative regulation of TCF-dependent signaling by WNT ligand antagonists, Presenilin action in Notch and Wnt signaling, Signal Transduction, which may be useful for your reference. Also, other proteins which involved in the same pathway with WIF1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Negative regulation of TCF-dependent signaling by WNT ligand antagonists
KREMEN2; KREMEN1; WIF1
Presenilin action in Notch and Wnt signaling
AES; TLE1; WIF1; KREMEN2
Signal Transduction
OTULIN; BCO2; NOTUM; UTS2D; CRABP2B; GMIP; OR56A1; WIF1; RYK; RGR
Signaling by Wnt
SOX6; PYGO1; SOX4A; TNKS2; KLHL12; FAM123B; PYGO2; RYK; SOX32; HECW1
TCF dependent signaling in response to WNT
SRY; CCDC88C; WNT8-2; SOX32; SOX7; RYK; HECW1; HECW1B; SOX13; SOX9B
Wnt signaling network
WIF1; RSPO1; ATP6AP2; CTHRC1; IGFBP4; RYK
Wnt signaling pathway
NKD2B; CTBP2A; RHOA; SFRP1; Fzd4; CUL1A; FRAT2; PRKACB; SFRP2; WNT3

Protein Function

WIF1 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by WIF1 itself. We selected most functions WIF1 had, and list some proteins which have the same functions with WIF1. You can find most of the proteins on our site.
Function
Related Protein
Function protein binding
Related Protein ALOX5; RAD51; NUS1; JAM3B; TRIM10; CDC42; SMR3B; ASAP3; KLK4; GUCY1A3

Interacting Protein

WIF1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with WIF1 here. Most of them are supplied by our site. Hope this information will be useful for your research of WIF1.
KRTAP10-8; Wnt5a; Wnt3a