Description : |
The protein encoded by this gene functions to inhibit WNT proteins, which are extracellular signaling molecules that play a role in embryonic development. This protein contains a WNT inhibitory factor (WIF) domain and five epidermal growth factor (EGF)-like domains, and is thought to be involved in mesoderm segmentation. This gene functions as a tumor suppressor gene, and has been found to be epigenetically silenced in various cancers. |
Source : |
HEK293 |
Species : |
Human |
Tag : |
His |
Form : |
Lyophilized from a 0.2 µM filtered solution of 10mM HAc-NaAc, 150mM NaCl, 0.5% CHAPS, pH 4.0 |
Molecular Mass : |
39.47kD |
AA Sequence : |
GPPQEESLYLWIDAHQARVLIGFEE DILIVSEGKMAPFTHDFRKAQQRMP AIPVNIHSMNFTWQAAGQAEYFYEF LSLRSLDKGIMADPTVNVPLLGTVP HKASVVQVGFPCLGKQDGVAAFEVD VIVMNSEGNTILKTPQNAIFFKTCQ QAECPGGCRNGGFCNERRICECPDG FHGPHCEKALCTPRCMNGGLCVTPG FCICPPGFYGVNCDKANCSTTCFNG GTCFYPGKCICPPGLEGEQCEISKC PQPCRNGGKCIGKSKCKCSKGYQGD LCSKPVCEPGCGAHGTCHEPNKCQC QEGWHGRHCNKRYEASLIHALRPAG AQLRQHTPSLKKAEERRDPPESNYI WVDHHHHHH |
Endotoxin : |
Endotoxin level is <0.1 ng/µg of protein (<1EU/µg). |
Purity : |
>95% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : |
Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |