ywhah
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  • Official Full Name
  • Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein, Eta Polypeptide
  • Background
  • This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat have been associated with early-onset schizophrenia and psychotic bipolar disorder.
  • Synonyms
  • YWHAH; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide; YWHA1; 14-3-3 eta; Protein AS1; 14-3-3 protein eta; OTTHUMP00000028905
Cat.#:YWHAH-139HTag:His
Source (Host):Insect cellsSpecies:Human
Product nameRecombinant Human YWHAH Protein, His-tagged
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Cat.#:YWHAH-141HTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human YWHAH Protein
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Cat.#:YWHAH-142HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human YWHAH Protein, GST-tagged
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Cat.#:YWHAH-143HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human YWHAH Protein, GST-tagged
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Cat.#:YWHAH-2562HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human YWHAH, GST tagged
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Cat.#:YWHAH-26005THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human YWHAH, His-tagged
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Cat.#:YWHAH-26007THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human YWHAH, His-tagged
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Cat.#:YWHAH-67HTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human YWHAH protein
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Cat.#:Ywhah-140MTag:His
Source (Host):Insect cellsSpecies:Mouse
Product nameRecombinant Mouse Ywhah Protein, His-tagged
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Cat.#:YWHAH-18685MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse YWHAH Protein
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Cat.#:YWHAH-6640RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat YWHAH Protein
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Cat.#:YWHAH-5248RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey YWHAH Protein, His-tagged
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Cat.#:YWHAH-1764CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken YWHAH
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Cat.#:YWHAH-12380ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish YWHAH
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Cat.#:YWHAH-231HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human YWHAH 293 Cell Lysate
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Involved Pathway

YWHAH involved in several pathways and played different roles in them. We selected most pathways YWHAH participated on our site, such as Cell cycle, Oocyte meiosis, PIK-Akt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with YWHAH were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cell cycle
INCENP; CENPO; H3F3D; TMPO; TGFB3; ABL1; NUPL2; ACTR1A; CENPE; MPEG1
Oocyte meiosis
CALM2B; PPP3R1; MAD2L2; SGOL1; BTRC; CALM3B; SMC1B; SLK; ANAPC11; ANAPC13
PIK-Akt signaling pathway
IFNA16; NOS3; OSMR; FGF8; PDGFB; MTCP1; LPAR3; PDGFRA; IFNA8; PPP2R2C
Hippo signaling pathway
INADL; PRKCZ; AFP; DLG3; JUB; GDF5; FZD10; LATS1; YWHAB; TGFBR2
Epstein-Barr virus infection
CSNK2A2; POLR1D; POLR3E; SFPI1; PSMD11; CD38; POLR3B; MAPK10; CCNA2; NFKBIB
Viral carcinogenesis
TRAF5; HIST1H2BE; KAT2A; STAT5B; GTF2A1L; BAD; MDM2; GTF2E1; ATF4; IRF7

Protein Function

YWHAH has several biochemical functions, for example, actin binding, enzyme binding, glucocorticoid receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by YWHAH itself. We selected most functions YWHAH had, and list some proteins which have the same functions with YWHAH. You can find most of the proteins on our site.
Function
Related Protein
Function actin binding
Related Protein PLECA; VCL; GBP1; CYFIP1; MAEA; SPTB; SHANK3; HPCA; WASF3B; SNTB2
Function enzyme binding
Related Protein TSPAN10; TSPAN5; CDK19; VAPB; CABYR; SORT1; AKIRIN2; DVL1; UGT1A6B; PGR
Function glucocorticoid receptor binding
Related Protein CEBPB; FKBP4; NR4A2; STAT5B; STAT3; EP300; NRIP1; YWHAH; GRIP1; ETS2
Function insulin-like growth factor receptor binding
Related Protein PIK3R1; SHC1; IGF2B; GNAS; YWHAH; INSR; SOCS1; IRS1; YWHAG; REN
Function ion channel binding
Related Protein SUMO1; PIRT; KCNIP2; ANK2; SNTA1; FGF12; PDE4D; NEDD4L; USP10; NOS1
Function protein binding
Related Protein PGR; CXXC1; SMAD4; STT3A; MFAP1; DHX9; CEP44; RRAGB; ABHD14B; DGAT1
Function protein domain specific binding
Related Protein CHMP1B; MRPS31; CACNB2; PRKAR2B; RXRA; SP100; HIST1H4E; SKI; HIST1H4N; WHRN
Function protein heterodimerization activity
Related Protein TTR; F11R.1; DMRT1; TAF12; PPP3CB; RRAGC; HIST1H4A; HIST1H2BN; NFYBB; HIST1H2AG
Function sodium channel regulator activity
Related Protein SCN2B; SGK2B; FGF13; NEDD4L; PRSS30; SCN1B; PKP2; SGK1; FXYD2; SGK2

Interacting Protein

YWHAH has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with YWHAH here. Most of them are supplied by our site. Hope this information will be useful for your research of YWHAH.
MARK2; RAF1; HDAC4; CDC25B