ywhah
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  • Official Full Name
  • Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein, Eta Polypeptide
  • Background
  • This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat have been associated with early-onset schizophrenia and psychotic bipolar disorder.
  • Synonyms
  • YWHAH; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide; YWHA1; 14-3-3 eta; Protein AS1; 14-3-3 protein eta; OTTHUMP00000028905
Cat.#:YWHAH-139HTag:His
Source (Host):Insect cellsSpecies:Human
Product nameRecombinant Human YWHAH Protein, His-tagged
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Cat.#:YWHAH-141HTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human YWHAH Protein
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Cat.#:YWHAH-142HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human YWHAH Protein, GST-tagged
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Cat.#:YWHAH-143HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human YWHAH Protein, GST-tagged
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Cat.#:YWHAH-2562HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human YWHAH, GST tagged
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Cat.#:YWHAH-26005THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human YWHAH, His-tagged
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Cat.#:YWHAH-26007THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human YWHAH, His-tagged
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Cat.#:YWHAH-67HTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human YWHAH protein
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Cat.#:Ywhah-140MTag:His
Source (Host):Insect cellsSpecies:Mouse
Product nameRecombinant Mouse Ywhah Protein, His-tagged
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Cat.#:YWHAH-18685MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse YWHAH Protein
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Cat.#:YWHAH-6640RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat YWHAH Protein
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Cat.#:YWHAH-5248RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey YWHAH Protein, His-tagged
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Cat.#:YWHAH-1764CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken YWHAH
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Cat.#:YWHAH-12380ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish YWHAH
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Cat.#:YWHAH-231HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human YWHAH 293 Cell Lysate
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Involved Pathway

YWHAH involved in several pathways and played different roles in them. We selected most pathways YWHAH participated on our site, such as Cell cycle, Oocyte meiosis, PIK-Akt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with YWHAH were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cell cycle
INCENP; CSNK2A1; CDCA8; HAUS2; RCC2; NINL; GINS3; ITGB3BP; NIPBL; CHEK1
Oocyte meiosis
PPP2R5EA; PPP2R5C; CDK1; SLK; IGF1RA; CAMK2G1; RPS6KA3A; CDC26; SMC1AL; ITPR3
PIK-Akt signaling pathway
COL6A6; IL3RA; ITGA7; TCL1; YWHAE; GNB1; RAF1; MAPK1; TRP53; VWF
Hippo signaling pathway
BMP4; CTGF; TEAD2; Fzd4; TEAD1; PPP2CA; YWHAH; BMP8A; GSK3B; MOB1A
Epstein-Barr virus infection
POLR2B; PTMA; TAB1; PSMC6; GTF2B; HLA-DQA2; H2-Q10; POLR2J; MAP2K3; PSMD1
Viral carcinogenesis
HIST1H2BA; TBPL1; HDAC8; EP300; RBPJ; HIST1H4L; PKM; MAPK1; PRKACG; HIST1H4B

Protein Function

YWHAH has several biochemical functions, for example, actin binding, enzyme binding, glucocorticoid receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by YWHAH itself. We selected most functions YWHAH had, and list some proteins which have the same functions with YWHAH. You can find most of the proteins on our site.
Function
Related Protein
Function actin binding
Related Protein MSN; MYO1H; GSNB; SSH3; MYH4; WIPF2B; ADD2; INPPL1B; EPS8L2; CNN1A
Function enzyme binding
Related Protein CAV1; C2orf56; DIS3L; ESR2; PPARG; Il6ra; Txn1; PARK2; CAD; ITGB3
Function glucocorticoid receptor binding
Related Protein ETS2; GRIP1; NRIP1; FKBP4; NR4A2; EP300; STAT3; YWHAH; STAT5B; CEBPB
Function insulin-like growth factor receptor binding
Related Protein Ren1; GNAS; REN; INS2; IGF1; INS; PIK3R1; ARRB1; IGF2; IGF3
Function ion channel binding
Related Protein RANGRF; PDE4B; AKAP6; KCNE1L; CHERP; PACS2; GPD1L; KCNJ11; RNF207; ACTN1
Function protein binding
Related Protein CALCOCO2; NELL2; LRPPRC; TMEM123; KCTD13; PCBD2; GAGE8; PRKAB2; PGF; BAG1
Function protein domain specific binding
Related Protein ARFIP2A; PTPN11; CRB3; ZNF521; LIN7B; IGBP1; ARFIP2B; YWHAE; PRKAR2B; YWHAZ
Function protein heterodimerization activity
Related Protein MEIS1; UGT1A1; KCNK3; H3F3C; GAD2; ADORA2A; FLOT1; PANX2; HIST1H2BL; CA
Function sodium channel regulator activity
Related Protein FXYD7; FXYD6; SCN1B; PRSS30; SGK1; RANGRF; FGF13; FGF12; SCN1BA; FXYD4

Interacting Protein

YWHAH has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with YWHAH here. Most of them are supplied by our site. Hope this information will be useful for your research of YWHAH.
MARK2; RAF1; HDAC4; CDC25B